The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

prothrombin
Synonyms

ec 3.4.21.5
ID

http://purl.obolibrary.org/obo/dinto_1008
Definition

Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C
definition source

DrugBank Database
Gene

f2
is inhibited by

http://purl.obolibrary.org/obo/dinto_DB00278

http://purl.obolibrary.org/obo/CHEBI_65172

http://purl.obolibrary.org/obo/CHEBI_70746

http://purl.obolibrary.org/obo/CHEBI_45906

http://purl.obolibrary.org/obo/dinto_DB02351

http://purl.obolibrary.org/obo/dinto_DB00001

http://purl.obolibrary.org/obo/CHEBI_59173
is pharmacological target of

http://purl.obolibrary.org/obo/dinto_DB00278

http://purl.obolibrary.org/obo/CHEBI_65172

http://purl.obolibrary.org/obo/CHEBI_70746

http://purl.obolibrary.org/obo/dinto_DB00001

http://purl.obolibrary.org/obo/CHEBI_59173
label

prothrombin
OrganismClass

human
prefixIRI

obo2:dinto_1008
prefLabel

prothrombin
related with

http://purl.obolibrary.org/obo/dinto_DB07400

http://purl.obolibrary.org/obo/dinto_DB07440

http://purl.obolibrary.org/obo/dinto_DB06858

http://purl.obolibrary.org/obo/dinto_DB08422

http://purl.obolibrary.org/obo/dinto_DB06850

http://purl.obolibrary.org/obo/dinto_DB04722

http://purl.obolibrary.org/obo/dinto_DB06854

http://purl.obolibrary.org/obo/dinto_DB07515

http://purl.obolibrary.org/obo/dinto_DB07366

http://purl.obolibrary.org/obo/dinto_DB07946

http://purl.obolibrary.org/obo/dinto_DB07165

http://purl.obolibrary.org/obo/dinto_DB07549

http://purl.obolibrary.org/obo/dinto_DB07353

http://purl.obolibrary.org/obo/dinto_DB07091

http://purl.obolibrary.org/obo/dinto_DB06861

http://purl.obolibrary.org/obo/dinto_DB06859

http://purl.obolibrary.org/obo/dinto_DB03136

http://purl.obolibrary.org/obo/dinto_DB02723

http://purl.obolibrary.org/obo/dinto_DB03159

http://purl.obolibrary.org/obo/dinto_DB06929

http://purl.obolibrary.org/obo/dinto_DB01766

http://purl.obolibrary.org/obo/dinto_DB06878

http://purl.obolibrary.org/obo/dinto_DB06869

http://purl.obolibrary.org/obo/dinto_DB08061

http://purl.obolibrary.org/obo/dinto_DB00100

http://purl.obolibrary.org/obo/dinto_DB00170

http://purl.obolibrary.org/obo/dinto_DB06947

http://purl.obolibrary.org/obo/dinto_DB02193

http://purl.obolibrary.org/obo/dinto_DB07508

http://purl.obolibrary.org/obo/dinto_DB03865

http://purl.obolibrary.org/obo/dinto_DB07718

http://purl.obolibrary.org/obo/dinto_DB06845

http://purl.obolibrary.org/obo/dinto_DB07376

http://purl.obolibrary.org/obo/dinto_DB07550

http://purl.obolibrary.org/obo/dinto_DB07211

http://purl.obolibrary.org/obo/dinto_DB04771

http://purl.obolibrary.org/obo/dinto_DB07944

http://purl.obolibrary.org/obo/dinto_DB07016

http://purl.obolibrary.org/obo/dinto_DB07897

http://purl.obolibrary.org/obo/dinto_DB06936

http://purl.obolibrary.org/obo/dinto_DB07190

http://purl.obolibrary.org/obo/dinto_DB07143

http://purl.obolibrary.org/obo/dinto_DB07133

http://purl.obolibrary.org/obo/dinto_DB06911

http://purl.obolibrary.org/obo/dinto_DB06841

http://purl.obolibrary.org/obo/dinto_DB08187

http://purl.obolibrary.org/obo/dinto_DB07277

http://purl.obolibrary.org/obo/dinto_DB07741

http://purl.obolibrary.org/obo/dinto_DB08254

http://purl.obolibrary.org/obo/dinto_DB07088

http://purl.obolibrary.org/obo/dinto_DB04772

http://purl.obolibrary.org/obo/dinto_DB06996

http://purl.obolibrary.org/obo/CHEBI_8452

http://purl.obolibrary.org/obo/dinto_DB07095

http://purl.obolibrary.org/obo/dinto_DB07131

http://purl.obolibrary.org/obo/dinto_DB08062

http://purl.obolibrary.org/obo/dinto_DB06868

http://purl.obolibrary.org/obo/dinto_DB07005

http://purl.obolibrary.org/obo/dinto_DB00055

http://purl.obolibrary.org/obo/dinto_DB07128

http://purl.obolibrary.org/obo/dinto_DB07658

http://purl.obolibrary.org/obo/dinto_DB06866

http://purl.obolibrary.org/obo/dinto_DB07278

http://purl.obolibrary.org/obo/dinto_DB07639

http://purl.obolibrary.org/obo/dinto_DB07809

http://purl.obolibrary.org/obo/dinto_DB06838

http://purl.obolibrary.org/obo/dinto_DB06919

http://purl.obolibrary.org/obo/dinto_DB07660

http://purl.obolibrary.org/obo/dinto_DB07279

http://purl.obolibrary.org/obo/dinto_DB07461

http://purl.obolibrary.org/obo/dinto_DB08546

http://purl.obolibrary.org/obo/dinto_DB07665

http://purl.obolibrary.org/obo/dinto_DB07659

http://purl.obolibrary.org/obo/dinto_DB04591

http://purl.obolibrary.org/obo/dinto_DB07796

http://purl.obolibrary.org/obo/dinto_DB07027

http://purl.obolibrary.org/obo/dinto_DB06942

http://purl.obolibrary.org/obo/dinto_DB07548

http://purl.obolibrary.org/obo/dinto_DB07522

http://purl.obolibrary.org/obo/dinto_DB06853

http://purl.obolibrary.org/obo/dinto_DB06865

http://purl.obolibrary.org/obo/dinto_DB07934

http://purl.obolibrary.org/obo/dinto_DB07120

http://purl.obolibrary.org/obo/dinto_DB03847

http://purl.obolibrary.org/obo/dinto_DB04697

http://purl.obolibrary.org/obo/dinto_DB00025

http://purl.obolibrary.org/obo/dinto_DB08624

http://purl.obolibrary.org/obo/dinto_DB07527

http://purl.obolibrary.org/obo/dinto_DB01767

http://purl.obolibrary.org/obo/dinto_DB04136

http://purl.obolibrary.org/obo/dinto_DB07083

http://purl.obolibrary.org/obo/dinto_DB08152

http://purl.obolibrary.org/obo/dinto_DB07105

http://purl.obolibrary.org/obo/dinto_DB07521
Synonym

ec 3.4.21.5

thrombin

coagulation factor ii

prothrombin precursor

activated factor ii [iia]
xref

UniProt ID:P00734

DrugBank:54
subClassOf

http://purl.obolibrary.org/obo/dinto_000130

http://purl.obolibrary.org/obo/dinto_000128
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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_8583 CHEBI LOOM
http://purl.obolibrary.org/obo/PR_000007299 OBA LOOM
http://purl.obolibrary.org/obo/CHEBI_8583 CHEBI LOOM
http://purl.obolibrary.org/obo/PR_000007299 OBA LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D08.622.709 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82273 NCIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D23.119.945 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#10259 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D011516 RH-MESH LOOM
http://purl.jp/bio/4/id/200906054614845014 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/1441688 RXNORM LOOM
http://www.co-ode.org/ontologies/galen#Prothrombin GALEN LOOM
http://www.phoc.org.cn/pmo/class/PMO_00019280 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/OMIT_0012460 OMIT LOOM
http://purl.bioontology.org/ontology/LNC/LP16010-8 LOINC LOOM
http://www.semanticweb.org/ontologies/STO.owl#c34c5b83_8e02_46b9_bb42_82651c32683a STO-DRAFT LOOM
http://www.semanticweb.org/ontologies/STO.owl#c34c5b83_8e02_46b9_bb42_82651c32683a CVAO LOOM
http://purl.obolibrary.org/obo/MESH_D011516 BERO LOOM
http://doe-generated-ontology.com/OntoAD#C0033706 ONTOAD LOOM
https://go.drugbank.com/drugs/DB11311 MDM LOOM
http://id.nlm.nih.gov/mesh/D011516 MDM LOOM
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571347974240596027 ACVD_ONTOLOGY LOOM
http://purl.obolibrary.org/obo/NCIT_C82854 BERO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0033706 OCHV LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82854 NCIT LOOM
http://purl.bioontology.org/ontology/MESH/D011516 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.124.125.800 RH-MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C82273 BERO LOOM
http://purl.bioontology.org/ontology/MEDDRA/10037038 MEDDRA LOOM
http://purl.uniprot.org/uniprot/P00734 FTC LOOM
http://purl.bioontology.org/ontology/CSP/0437-7626 CRISP LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01469 MIO LOOM
http://purl.obolibrary.org/obo/CHEBI_8583 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_8583 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_8583 DRON LOOM
http://purl.obolibrary.org/obo/PR_000007299 PR LOOM
http://purl.obolibrary.org/obo/PR_000007299 INBANCIDO LOOM
http://purl.obolibrary.org/obo/PR_000007299 HUPSON LOOM
http://purl.obolibrary.org/obo/PR_000007299 CIDO LOOM
http://purl.obolibrary.org/obo/PR_000007299 NIFSTD LOOM