The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Preferred Name	lidocaine
Synonyms	Lidoderm C14H22N2O 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide alpha-diethylamino-2,6-dimethylacetanilide 2-(Diethylamino)-2',6'-acetoxylidide N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide Lidocaine
ID	http://purl.obolibrary.org/obo/CHEBI_6456
AHFScode	72:00.00 52:16.00 24:04.04 84:08.00 24:04.04.08
ATCCode	S02DA01 S01HA07 R02AD02 D04AB01 A01AD11 C05AD01 C01BB01 N01BB02
binds	http://purl.obolibrary.org/obo/dinto_1670 http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2913 http://purl.obolibrary.org/obo/dinto_4078 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_2789 http://purl.obolibrary.org/obo/dinto_2792 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_2496 http://purl.obolibrary.org/obo/dinto_1956 http://purl.obolibrary.org/obo/dinto_1959 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_0465
blocks	http://purl.obolibrary.org/obo/dinto_2792
CASRN	137-58-6
DBBrand	rocephin kit after burn double strength gel dermaflex dalcaine alphacaine zilactin-l xylocaine dental ointment after burn spray solarcaine aloe extra burn relief cream xylocaine-mpf xylocaine solcain xylocaine endotracheal gravocain lignocaine xylocaine viscous lidoject-2 solarcaine leostesin anestacon jelly isicaina esracaine octocaine-50 duncaine xylocaine 5% spinal xylocaine test dose anestacon xylocard xylocaine-mpf with glucose lidoderm norwood sunburn spray zingo after burn double strength spray octocaine-100 lanabiotic after burn gel maricaine lidoject-1 octocaine cappicaine
DBname	lidocaine
DBSynonym	dilocaine l-caine
Definition	The amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000879 http://purl.obolibrary.org/obo/OAE_0000303 http://purl.obolibrary.org/obo/OAE_0000604 http://purl.obolibrary.org/obo/OAE_0001505 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000617 http://purl.obolibrary.org/obo/OAE_0000301 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000443 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0001369 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000677 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000476 http://purl.obolibrary.org/obo/OAE_0001538 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000539 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000454 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000687 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000438 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000898 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0000194 http://purl.obolibrary.org/obo/OAE_0000185 http://purl.obolibrary.org/obo/OAE_0000516 http://purl.obolibrary.org/obo/OAE_0001291 http://purl.obolibrary.org/obo/OAE_0000881 http://purl.obolibrary.org/obo/OAE_0000394
has pharmacological target	http://purl.obolibrary.org/obo/dinto_1670 http://purl.obolibrary.org/obo/dinto_2913 http://purl.obolibrary.org/obo/dinto_4078
has role	http://purl.obolibrary.org/obo/CHEBI_38070 http://purl.obolibrary.org/obo/CHEBI_36333
InChI	InChI=1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
InChIKey	InChIKey=NNJVILVZKWQKPM-UHFFFAOYSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_1670 http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2913 http://purl.obolibrary.org/obo/dinto_4078 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_2789
is metabolised by	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_2496 http://purl.obolibrary.org/obo/dinto_1956 http://purl.obolibrary.org/obo/dinto_1959 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_0465
is substrate of	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_2496 http://purl.obolibrary.org/obo/dinto_1956 http://purl.obolibrary.org/obo/dinto_1959 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_0465
label	lidocaine
may interact with	http://purl.obolibrary.org/obo/CHEBI_8214 http://purl.obolibrary.org/obo/CHEBI_32250 http://purl.obolibrary.org/obo/CHEBI_41774 http://purl.obolibrary.org/obo/CHEBI_37924 http://purl.obolibrary.org/obo/CHEBI_8499 http://purl.obolibrary.org/obo/CHEBI_4856 http://purl.obolibrary.org/obo/dinto_DB00857 http://purl.obolibrary.org/obo/CHEBI_3127 http://purl.obolibrary.org/obo/CHEBI_3699 http://purl.obolibrary.org/obo/dinto_DB00373 http://purl.obolibrary.org/obo/CHEBI_3441 http://purl.obolibrary.org/obo/CHEBI_9654 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/CHEBI_2904 http://purl.obolibrary.org/obo/dinto_DB01359 http://purl.obolibrary.org/obo/CHEBI_6904 http://purl.obolibrary.org/obo/CHEBI_9622 http://purl.obolibrary.org/obo/CHEBI_9398 http://purl.obolibrary.org/obo/CHEBI_63629 http://purl.obolibrary.org/obo/CHEBI_2379 http://purl.obolibrary.org/obo/dinto_DB00382 http://purl.obolibrary.org/obo/dinto_DB01580 http://purl.obolibrary.org/obo/CHEBI_7444 http://purl.obolibrary.org/obo/dinto_DB01369 http://purl.obolibrary.org/obo/CHEBI_6343 http://purl.obolibrary.org/obo/CHEBI_367163 http://purl.obolibrary.org/obo/dinto_DB01623 http://purl.obolibrary.org/obo/dinto_DB00976
modulates	http://purl.obolibrary.org/obo/dinto_2792
prefixIRI	obo2:CHEBI_6456
prefLabel	lidocaine
SMILES	CCN(CC)CC(=O)Nc1c(C)cccc1C CCN(CC)CC(=O)NC1=C(C)C=CC=C1C
Synonym	Lidoderm C14H22N2O 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide alpha-diethylamino-2,6-dimethylacetanilide 2-(Diethylamino)-2',6'-acetoxylidide N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide Lidocaine
xref	Patent:US2441498 KEGG DRUG:D00358 Drugs Product Database (DPD):712884 Patent:GB758224 DrugBank:DB00281 Wikipedia:Lidocaine Patent:GB706409 ChEMBL:106723 ChEBI:6456 IUPHAR:2623 Beilstein:2215784 Wikipedia:http://en.wikipedia.org/wiki/Lidocaine NIST Chemistry WebBook:137-58-6 National Drug Code Directory:21695-075-30 CASRN:137-58-6 PharmGKB:PA450226 Guide To Pharmacology:2623 PubChem Substance:46505060 RxList:http://www.rxlist.com/cgi/generic2/xylocaineinj.htm CiteXplore:11431418 PubChem Compound:3676 ChemSpider:3548 Drugs.com:http://www.drugs.com/cdi/lidocaine-gel.html
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_6456	DOID	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6456	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6456	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6456	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6456	OBIB	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6456	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6456	HHEAR	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6456	DDSS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6456	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6456	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6456	ECTO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6456	DOID	LOOM
http://purl.obolibrary.org/obo/CHEBI_6456	DRON	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.199.092.500	RH-MESH	LOOM
http://www.drugbank.ca/drugs/DB00281	FTC	LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Lidocaine	APAONTO	LOOM
https://bioportal.bioontology.org/ontologies/STMSO#lidocaine	STMSO	LOOM
http://purl.bioontology.org/ontology/ATC/N01BB02	ATC	LOOM
rgo:15230	GAMUTS	LOOM
http://purl.bioontology.org/ontology/CPT/80176	CPT	LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass00a8e53b_c982_4dcf_87cd_d0535154c7cf	WWECA	LOOM
http://purl.bioontology.org/ontology/ATC/S01HA07	ATC	LOOM
http://purl.bioontology.org/ontology/CSP/2268-8146	CRISP	LOOM
https://go.drugbank.com/drugs/DB00281	MDM	LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00672	COID	LOOM
http://stirdf.jst.go.jp/id/200907039328697134	IOBC	LOOM
http://purl.obolibrary.org/obo/OMIT_0009097	OMIT	LOOM
http://purl.bioontology.org/ontology/MESH/D008012	MESH	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387480006	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/ATC/C05AD01	ATC	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015827	PMAPP-PMO	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000146592	OCVDAE	LOOM
http://purl.bioontology.org/ontology/ATC/R02AD02	ATC	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C614	NCIT	LOOM
http://purl.obolibrary.org/obo/NCIT_C614	BERO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0023660	OCHV	LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02179	MIO	LOOM
http://purl.bioontology.org/ontology/SNMI/C-80400	SNMI	LOOM
http://purl.bioontology.org/ontology/ATC/C01BB01	ATC	LOOM
http://purl.bioontology.org/ontology/ATC/D04AB01	ATC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#7408	OCHV	LOOM
http://purl.obolibrary.org/obo/MESH_D008012	BERO	LOOM
http://www.radlex.org/RID/RID49907	RADLEX	LOOM
http://purl.bioontology.org/ontology/ATC/S02DA01	ATC	LOOM
http://purl.bioontology.org/ontology/VANDF/4018262	VANDF	LOOM
http://purl.bioontology.org/ontology/RXNORM/6387	RXNORM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008012	RH-MESH	LOOM
http://purl.obolibrary.org/obo/CHEBI_6456	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_6456	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_6456	OBIB	LOOM
http://purl.obolibrary.org/obo/CHEBI_6456	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_6456	HHEAR	LOOM
http://purl.obolibrary.org/obo/CHEBI_6456	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_6456	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_6456	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_6456	ECTO	LOOM
http://purl.bioontology.org/ontology/LNC/LP16174-2	LOINC	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146592	NDFRT	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU005009	LOINC	LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClassb7a1a033_659f_4395_ab08_04274ef0b7cb	WWECA	LOOM
http://purl.jp/bio/4/id/200906050976937868	IOBC	LOOM