The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

telbivudine
Synonyms

C10H14N2O5

L-deoxythymidine

Epavudine

telbivudine

Beta-l-thymidine

2'-Deoxy-L-thymidine

beta-L-2'-deoxythymidine

L-DT

L-thymidine

LDT

1-(2-deoxy-beta-L-ribofuranosyl)-5-methyluracil

1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

1-(2-deoxy-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione

ID

http://purl.obolibrary.org/obo/CHEBI_63624

AHFScode

08:18.08.20

ATCCode

J05AF11

binds

http://purl.obolibrary.org/obo/dinto_2873

http://purl.obolibrary.org/obo/dinto_3880

CASRN

3424-98-4

DBBrand

sebivo

tyzeka

DBname

telbivudine

DBSynonym

l-deoxythymidine

epavudine

ldt

telbivudin

beta-l-thymidine

2'-deoxy-l-thymidine

l-dt

l-thymidine

Definition

A pyrimidine 2'-deoxyribonucleoside that is the L-enantiomer of thymine. A synthetic thymidine nucleoside analogue with activity against HBV DNA polymerase.

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2873

http://purl.obolibrary.org/obo/dinto_3880

has role

http://purl.obolibrary.org/obo/CHEBI_59897

http://purl.obolibrary.org/obo/CHEBI_36044

InChI

InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1

InChIKey

InChIKey=IQFYYKKMVGJFEH-CSMHCCOUSA-N

label

telbivudine

prefixIRI

obo2:CHEBI_63624

prefLabel

telbivudine

related with

http://purl.obolibrary.org/obo/dinto_2873

http://purl.obolibrary.org/obo/dinto_3880

SMILES

Cc1cn([C@@H]2C[C@@H](O)[C@H](CO)O2)c(=O)[nH]c1=O

CC1=CN([C@@H]2C[C@@H](O)[C@H](CO)O2)C(=O)NC1=O

Synonym

C10H14N2O5

L-deoxythymidine

Epavudine

telbivudine

Beta-l-thymidine

2'-Deoxy-L-thymidine

beta-L-2'-deoxythymidine

L-DT

L-thymidine

LDT

1-(2-deoxy-beta-L-ribofuranosyl)-5-methyluracil

1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

1-(2-deoxy-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione

xref

BindingDB:50156567

ChemSpider:140081

CiteXplore:22257108

CiteXplore:21703206

CiteXplore:21457439

RxList:http://www.rxlist.com/cgi/generic/tyzeka.htm

CiteXplore:21147187

National Drug Code Directory:0078-0539-85

PharmGKB:PA164760861

CiteXplore:21040410

Drugs Product Database (DPD):2288389

CiteXplore:22132702

DrugBank:DB01265

CiteXplore:22233255

PubChem Substance:46508706

CiteXplore:21642814

CASRN:3424-98-4

CiteXplore:22093034

CiteXplore:22174039

PubChem Compound:159269

CiteXplore:21670922

ChEMBL:466271

CiteXplore:21748522

CiteXplore:21586234

Reaxys:754297

Drugs.com:http://www.drugs.com/cdi/telbivudine.html

KEGG DRUG:D06675

Wikipedia:Telbivudine

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_63624 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63624 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63624 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63624 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63624 FB-CV SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63624 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63624 UPHENO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63624 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63624 FYPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63624 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_63624 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_63624 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_63624 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_63624 FB-CV LOOM
http://purl.obolibrary.org/obo/CHEBI_63624 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_63624 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_63624 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_63624 FYPO LOOM
http://stirdf.jst.go.jp/id/200907094943269240 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000176071 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C487779 RH-MESH LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000176071 ODAE LOOM
http://purl.bioontology.org/ontology/VANDF/4025782 VANDF LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66584 NCIT LOOM
http://purl.bioontology.org/ontology/ATC/J05AF11 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D000077712 MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/474128 RXNORM LOOM
http://purl.obolibrary.org/obo/DRON_00019582 ODNAE LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026008 PMAPP-PMO LOOM
https://go.drugbank.com/drugs/DB01265 MDM LOOM
http://purl.bioontology.org/ontology/LNC/LP96214-9 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU034725 LOINC LOOM
http://purl.obolibrary.org/obo/NCIT_C66584 BERO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/425347005 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000671737 PDQ LOOM
http://purl.jp/bio/4/id/200906000166466977 IOBC LOOM