The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Preferred Name	ribavirin
Synonyms	ribavirinum 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide ribavirine 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide RBV C8H12N4O5 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide ribavirin ribavirina
ID	http://purl.obolibrary.org/obo/CHEBI_63580
AHFScode	08:18.32
altId	CHEBI:8840
ATCCode	J05AB04
binds	http://purl.obolibrary.org/obo/dinto_2809 http://purl.obolibrary.org/obo/dinto_0383 http://purl.obolibrary.org/obo/dinto_1148 http://purl.obolibrary.org/obo/dinto_2873 http://purl.obolibrary.org/obo/dinto_0275 http://purl.obolibrary.org/obo/dinto_2090 http://purl.obolibrary.org/obo/dinto_3526 http://purl.obolibrary.org/obo/dinto_0718 http://purl.obolibrary.org/obo/dinto_1885
blocks	http://purl.obolibrary.org/obo/dinto_3526
CASRN	36791-04-5
DBBrand	ribamide ribamidyl rebetron varazid virazid ribavirin-tp rebretron ribasphere ribav tribavirin rebetol rtca viramid ribamidil vilona copegus ribavirin capsules virazole rtc
DBname	ribavirin
DBSynonym	ribavirinum [inn-latin] rbv ribavirina [inn-spanish] ribavirine [inn-french]
Definition	A 1-ribosyltriazole that is the 1-ribofuranosyl derivative of 1,2,4-triazole-3-carboxamide. An inhibitor of HCV polymerase.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000901 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000817 http://purl.obolibrary.org/obo/OAE_0000905 http://purl.obolibrary.org/obo/OAE_0001154 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000839 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000335 http://purl.obolibrary.org/obo/OAE_0001744 http://purl.obolibrary.org/obo/OAE_0000267 http://purl.obolibrary.org/obo/OAE_0000596 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0001167 http://purl.obolibrary.org/obo/OAE_0000411 http://purl.obolibrary.org/obo/OAE_0001481 http://purl.obolibrary.org/obo/OAE_0000443 http://purl.obolibrary.org/obo/OAE_0001431 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0000801 http://purl.obolibrary.org/obo/OAE_0001369 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000549 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000545 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000577 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0001229 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000476 http://purl.obolibrary.org/obo/OAE_0000915 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000103 http://purl.obolibrary.org/obo/OAE_0001053 http://purl.obolibrary.org/obo/OAE_0000518 http://purl.obolibrary.org/obo/OAE_0001063 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0001026 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000632 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0001433 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0001340 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0001105 http://purl.obolibrary.org/obo/OAE_0000084 http://purl.obolibrary.org/obo/OAE_0000100 http://purl.obolibrary.org/obo/OAE_0000434 http://purl.obolibrary.org/obo/OAE_0001308 http://purl.obolibrary.org/obo/OAE_0000587 http://purl.obolibrary.org/obo/OAE_0000286 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000475 http://purl.obolibrary.org/obo/OAE_0000643 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000533 http://purl.obolibrary.org/obo/OAE_0000674 http://purl.obolibrary.org/obo/OAE_0000613 http://purl.obolibrary.org/obo/OAE_0000894 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0001164 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0002122 http://purl.obolibrary.org/obo/OAE_0001343 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0001256 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0001336 http://purl.obolibrary.org/obo/OAE_0000022 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000491 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000487 http://purl.obolibrary.org/obo/OAE_0001052 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001345 http://purl.obolibrary.org/obo/OAE_0000296 http://purl.obolibrary.org/obo/OAE_0000501 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000358 http://purl.obolibrary.org/obo/OAE_0001035 http://purl.obolibrary.org/obo/OAE_0000618 http://purl.obolibrary.org/obo/OAE_0000488 http://purl.obolibrary.org/obo/OAE_0000480 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000350
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2809 http://purl.obolibrary.org/obo/dinto_3526 http://purl.obolibrary.org/obo/dinto_0275
has role	http://purl.obolibrary.org/obo/CHEBI_35441 http://purl.obolibrary.org/obo/CHEBI_35221 http://purl.obolibrary.org/obo/CHEBI_59897 http://purl.obolibrary.org/obo/CHEBI_22587
InChI	InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
InChIKey	InChIKey=IWUCXVSUMQZMFG-AFCXAGJDSA-N
induces	http://purl.obolibrary.org/obo/dinto_2090
inhibits	http://purl.obolibrary.org/obo/dinto_2809 http://purl.obolibrary.org/obo/dinto_0383 http://purl.obolibrary.org/obo/dinto_1148
is metabolised by	http://purl.obolibrary.org/obo/dinto_0275
is substrate of	http://purl.obolibrary.org/obo/dinto_0275 http://purl.obolibrary.org/obo/dinto_0718 http://purl.obolibrary.org/obo/dinto_1885
is transported by	http://purl.obolibrary.org/obo/dinto_0718 http://purl.obolibrary.org/obo/dinto_1885
label	ribavirin
modulates	http://purl.obolibrary.org/obo/dinto_3526
prefixIRI	obo2:CHEBI_63580
prefLabel	ribavirin
related with	http://purl.obolibrary.org/obo/dinto_2873 http://purl.obolibrary.org/obo/dinto_0275
SMILES	NC(=O)C1=NN(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O NC(=O)c1ncn(n1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Synonym	ribavirinum 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide ribavirine 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide RBV C8H12N4O5 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide ribavirin ribavirina
xref	Drugs.com:http://www.drugs.com/cdi/ribavirin.html CiteXplore:22052088 CiteXplore:22156853 RxList:www.rxlist.com/cgi/generic2/ribavirin.htm CiteXplore:22052220 CiteXplore:22239511 CiteXplore:22212568 CiteXplore:22212566 Wikipedia:Ribavirin PDB:RTP National Drug Code Directory:0004-0086-94 DrugBank:DB00811 CiteXplore:22212576 CiteXplore:22158703 PubChem Substance:46505883 Reaxys:892462 Wikipedia:http://en.wikipedia.org/wiki/Ribavirin CiteXplore:22212572 CASRN:892462 CASRN:36791-04-5 KEGG DRUG:D00423 CiteXplore:22239498 ChEMBL:585738 CiteXplore:22212569 CiteXplore:22212579 CiteXplore:22220723 PubChem Compound:37542 ChemSpider:34439 CiteXplore:21827730 PharmGKB:PA451241
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_63580	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63580	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63580	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63580	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63580	INBANCIDO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63580	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63580	COVID-19	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63580	GO-PLUS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63580	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63580	DDSS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63580	CIDO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63580	ECTO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63580	ODNAE	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63580	OBA	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63580	DRON	LOOM
http://www.drugbank.ca/drugs/DB00811	FTC	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C807	NCIT	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147496	NDFRT	LOOM
http://purl.bioontology.org/ontology/RXNORM/9344	RXNORM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D012254	RH-MESH	LOOM
http://purl.obolibrary.org/obo/CHEBI_63580	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_63580	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_63580	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_63580	INBANCIDO	LOOM
http://purl.obolibrary.org/obo/CHEBI_63580	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_63580	COVID-19	LOOM
http://purl.obolibrary.org/obo/CHEBI_63580	GO-PLUS	LOOM
http://purl.obolibrary.org/obo/CHEBI_63580	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_63580	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_63580	CIDO	LOOM
http://purl.obolibrary.org/obo/CHEBI_63580	ECTO	LOOM
http://purl.obolibrary.org/obo/CHEBI_63580	ODNAE	LOOM
http://purl.obolibrary.org/obo/CHEBI_63580	OBA	LOOM
http://purl.bioontology.org/ontology/CSP/2109-4100	CRISP	LOOM
http://purl.bioontology.org/ontology/SNMI/C-55B40	SNMI	LOOM
http://purl.bioontology.org/ontology/ATC/J05AP01	ATC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#10875	OCHV	LOOM
https://go.drugbank.com/drugs/DB00811	MDM	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0035525	OCHV	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387188005	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/LNC/LP35809-0	LOINC	LOOM
http://purl.bioontology.org/ontology/MESH/D012254	MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D13.570.800.790	RH-MESH	LOOM
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Ribavirin	SEPON	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147496	INBANCIDO	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147496	ODAE	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147496	CIDO	LOOM
http://purl.obolibrary.org/obo/OMIT_0013168	OMIT	LOOM
http://purl.obolibrary.org/obo/NCIT_C807	BERO	LOOM
http://stirdf.jst.go.jp/id/200907077787577914	IOBC	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU018696	LOINC	LOOM
http://purl.jp/bio/4/id/200906093594012822	IOBC	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00024072	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/VANDF/4019299	VANDF	LOOM
http://purl.obolibrary.org/obo/MESH_D012254	BERO	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000040325	PDQ	LOOM