The hydrochloride salt of fenfluramine. It binds to the serotonin reuptake pump, causing inhbition of serotonin uptake and release of serotonin. The resulting increased levels of serotonin lead to greater serotonin receptor activation which in turn lead to enhancement of serotoninergic transmission in the centres of feeding behavior located in the hypothalamus. This suppresses the appetite for carbohydrates. Fenfluramine hydrochloride was used for treatment of diabetes and obesity. It was withdrawn worldwide after reports of heart valve disease and pulmonary hypertension.

InChI=1S/C12H16F3N.ClH/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15;/h4-6,8-9,16H,3,7H2,1-2H3;1H

InChIKey=ZXKXJHAOUFHNAS-UHFFFAOYSA-N

fenfluramine hydrochloride

obo2:CHEBI_59729

fenfluramine hydrochloride

[Cl-].CC[NH2+]C(C)Cc1cccc(c1)C(F)(F)F

C12H17ClF3N

N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-aminium chloride

fenfluramine HCl

N-ethyl-alpha-methyl-m-(trifluoromethyl)phenethylamine hydrochloride

N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine hydrochloride

(+-)-fenfluramine HCl

1-(3-trifluoromethylphenyl)-2-ethylaminopropane hydrochloride

NN-ethyl-alpha-methyl-3-trifluoromethylphenethylamine hydrochloride

(+-)-fenfluramine hydrochloride

ChEMBL:1478487

DrugBank:DB00574

Beilstein:5652886

CASRN:404-82-0

KEGG DRUG:D04148