The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

glyburide
Synonyms

glibenclamidum

1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea

Glynase

1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea

Diabeta

Glyburide

5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide

5-chloro-N-(2-{4-[N-(N-cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide

glibenclamida

C23H28ClN3O5S

5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide

glibenclamide

Micronase

ID

http://purl.obolibrary.org/obo/CHEBI_5441

AHFScode

68:20.20

ATCCode

A10BB01

binds

http://purl.obolibrary.org/obo/dinto_2142

http://purl.obolibrary.org/obo/dinto_0156

http://purl.obolibrary.org/obo/dinto_3464

http://purl.obolibrary.org/obo/dinto_0588

http://purl.obolibrary.org/obo/dinto_1977

http://purl.obolibrary.org/obo/dinto_0887

http://purl.obolibrary.org/obo/dinto_0883

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_4065

http://purl.obolibrary.org/obo/dinto_2004

http://purl.obolibrary.org/obo/dinto_1987

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_3489

http://purl.obolibrary.org/obo/dinto_2820

http://purl.obolibrary.org/obo/dinto_2828

http://purl.obolibrary.org/obo/dinto_3338

http://purl.obolibrary.org/obo/dinto_0520

http://purl.obolibrary.org/obo/dinto_3643

http://purl.obolibrary.org/obo/dinto_0217

http://purl.obolibrary.org/obo/dinto_0341

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_1322

blocks

http://purl.obolibrary.org/obo/dinto_0341

CASRN

10238-21-8

DBBrand

glibenbeta

dia-basan

glibenclamid basics

bastiverit

normoglucon

adiab

glycolande

tiabet

glitisol

orabetic

prestab

gen-glybe

glucomid

malix

glibenclamid genericon

glibenil

suraben

glibenclamid riker m.

benclamin

gbn 5

lisaglucon

glucohexal

glibenclamid-cophar

gluben

lederglib

diabiphage

glynase

euglucon

gliboral

glimide

glycomin

glibil

betanase

dibelet

glibenclamid heumann

daonil

micronase

gliben-puren n

glidiabet

gewaglucon

betanese 5

glybenclamide

glibenclamid fabra

glybenzcyclamide

glyben

diabeta

glibetic

glimel

glibadone

gliban

glibenclamid-ratiopharm

glamide

euglucan

maninil

glicem

glibesyn

glibet

abbenclamide

pira

glucoven

prodiabet

renabetic

euglykon

glucolon

glibenclamid al

gliben

norglicem 5

euclamin

cytagon

debtan

hexaglucon

libanil

gilemal

nadib

glubate

semi-daonil

glisulin

glucobene

calabren

euglucon 5

novo-glyburide

praeciglucon

sugril

duraglucon

med-glionil

azuglucon

yuglucon

neogluconin

melix

gluco-tablimen

glimidstata

glucoremed

humedia

glibens

miglucan

DBname

glyburide

DBSynonym

glibenclamidum [inn-latin]

glibenclamida [inn-spanish]

apo-glibenclamide

glibenclamide

Definition

An urea that has formula C23H28ClN3O5S.

has effect

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0001026

http://purl.obolibrary.org/obo/OAE_0000287

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000551

http://purl.obolibrary.org/obo/OAE_0001275

http://purl.obolibrary.org/obo/OAE_0001295

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0001106

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0000487

http://purl.obolibrary.org/obo/OAE_0000565

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000811

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2142

has role

http://purl.obolibrary.org/obo/CHEBI_38070

http://purl.obolibrary.org/obo/CHEBI_35526

InChI

InChI=1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29)

InChIKey

InChIKey=ZNNLBTZKUZBEKO-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_0588

http://purl.obolibrary.org/obo/dinto_1977

http://purl.obolibrary.org/obo/dinto_0887

http://purl.obolibrary.org/obo/dinto_0883

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_4065

http://purl.obolibrary.org/obo/dinto_2004

http://purl.obolibrary.org/obo/dinto_1987

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_3489

http://purl.obolibrary.org/obo/dinto_2820

http://purl.obolibrary.org/obo/dinto_2828

http://purl.obolibrary.org/obo/dinto_3338

http://purl.obolibrary.org/obo/dinto_0520

http://purl.obolibrary.org/obo/dinto_3643

is metabolised by

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_0901

is substrate of

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_0883

http://purl.obolibrary.org/obo/dinto_1322

is transported by

http://purl.obolibrary.org/obo/dinto_0883

http://purl.obolibrary.org/obo/dinto_1322

label

glyburide

may interact with

http://purl.obolibrary.org/obo/CHEBI_8214

http://purl.obolibrary.org/obo/dinto_DB01401

http://purl.obolibrary.org/obo/dinto_DB01399

http://purl.obolibrary.org/obo/CHEBI_3437

http://purl.obolibrary.org/obo/dinto_DB01296

http://purl.obolibrary.org/obo/CHEBI_8499

http://purl.obolibrary.org/obo/dinto_DB01397

http://purl.obolibrary.org/obo/dinto_DB01294

http://purl.obolibrary.org/obo/CHEBI_4856

http://purl.obolibrary.org/obo/CHEBI_4031

http://purl.obolibrary.org/obo/CHEBI_15365

http://purl.obolibrary.org/obo/CHEBI_3750

http://purl.obolibrary.org/obo/CHEBI_63622

http://purl.obolibrary.org/obo/CHEBI_3127

http://purl.obolibrary.org/obo/dinto_DB00373

http://purl.obolibrary.org/obo/CHEBI_238698

http://purl.obolibrary.org/obo/CHEBI_17698

http://purl.obolibrary.org/obo/CHEBI_3441

http://purl.obolibrary.org/obo/CHEBI_59594

http://purl.obolibrary.org/obo/CHEBI_2904

http://purl.obolibrary.org/obo/dinto_DB01359

http://purl.obolibrary.org/obo/CHEBI_6904

http://purl.obolibrary.org/obo/CHEBI_48574

http://purl.obolibrary.org/obo/dinto_DB00052

http://purl.obolibrary.org/obo/CHEBI_2379

http://purl.obolibrary.org/obo/CHEBI_3082

http://purl.obolibrary.org/obo/dinto_DB01580

http://purl.obolibrary.org/obo/CHEBI_7444

http://purl.obolibrary.org/obo/CHEBI_4513

http://purl.obolibrary.org/obo/CHEBI_51450

http://purl.obolibrary.org/obo/CHEBI_4495

http://purl.obolibrary.org/obo/CHEBI_6343

http://purl.obolibrary.org/obo/CHEBI_28077

http://purl.obolibrary.org/obo/CHEBI_258351

http://purl.obolibrary.org/obo/dinto_DB01398

modulates

http://purl.obolibrary.org/obo/dinto_2142

http://purl.obolibrary.org/obo/dinto_0156

http://purl.obolibrary.org/obo/dinto_3464

http://purl.obolibrary.org/obo/dinto_0341

prefixIRI

obo2:CHEBI_5441

prefLabel

glyburide

related with

http://purl.obolibrary.org/obo/dinto_0217

SMILES

COC1=C(C=C(Cl)C=C1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1

COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1

Synonym

glibenclamidum

1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea

Glynase

1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea

Diabeta

Glyburide

5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide

5-chloro-N-(2-{4-[N-(N-cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide

glibenclamida

C23H28ClN3O5S

5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide

glibenclamide

Micronase

xref

ChemSpider:3368

Wikipedia:http://en.wikipedia.org/wiki/Glibenclamide

National Drug Code Directory:0378-1113-01

Beilstein:2230085

CASRN:10238-21-8

Drugs Product Database (DPD):2248008

RxList:http://www.rxlist.com/cgi/generic/glybur.htm

ChEMBL:105582

Guide To Pharmacology:2414

PharmGKB:PA449782

Patent:NL6603398

KEGG COMPOUND:C07022

Wikipedia:Glyburide

PubChem Substance:46509154

Patent:US3454635

Patent:NL6610580

DrugBank:DB01016

IUPHAR:2414

KEGG DRUG:D00336

ChEBI:5441

PubChem Compound:3488

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_5441 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5441 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5441 FIDEO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5441 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5441 HOIP SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5441 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5441 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5441 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5441 TXPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5441 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5441 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5441 ECTO SAME_URI
http://www.semanticweb.org/khaled/ontologies/2024/7/CDMOnto#Glyburide CDMONTO LOOM
http://purl.bioontology.org/ontology/MESH/D005905 MESH LOOM
http://purl.obolibrary.org/obo/MESH_D005905 BERO LOOM
http://purl.bioontology.org/ontology/LNC/LP14720-4 LOINC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146417 NDFRT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/384978002 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/CHEBI_5441 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_5441 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_5441 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_5441 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_5441 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_5441 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_5441 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_5441 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_5441 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_5441 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_5441 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_5441 ECTO LOOM
http://purl.obolibrary.org/obo/NCIT_C29076 BERO LOOM
http://purl.bioontology.org/ontology/SNMI/C-A2440 SNMI LOOM
http://www.drugbank.ca/drugs/DB01016 FTC LOOM
http://purl.obolibrary.org/obo/OMIT_0007100 OMIT LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000772960 PDQ LOOM
http://mimi.case.edu/ontologies/2009/9/DrugOntology#glyburide SDO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU062932 LOINC LOOM
http://purl.bioontology.org/ontology/CSP/2841-5600 CRISP LOOM
http://purl.bioontology.org/ontology/VANDF/4018078 VANDF LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29076 NCIT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0017628 OCHV LOOM
http://purl.bioontology.org/ontology/NDDF/000912 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.948.828.575 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/4815 RXNORM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#5521 OCHV LOOM
https://go.drugbank.com/drugs/DB01016 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.590.795.575 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017437 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D005905 RH-MESH LOOM