| Synonyms |
{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid
Aconip
2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid
C19H16ClNO4
[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
Indocin
indometacinum
indometacine
indometacina
indometacin
1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
Indomethacin
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| Definition |
A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
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| InChI |
InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
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| Synonym |
{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid Aconip 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid C19H16ClNO4 [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid Indocin indometacinum indometacine indometacina indometacin 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid Indomethacin
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| xref |
ChEMBL:100173 MetaCyc:CPD-10545 Reaxys:497341 CiteXplore:23992308 KEGG DRUG:D00141 Wikipedia:http://en.wikipedia.org/wiki/Indomethacin Patent:BE379378 CiteXplore:6039425 Drugs.com:http://www.drugs.com/cdi/indomethacin.html PharmGKB:PA449982 Gmelin:1446006 PDBeChem:IMN Beilstein:497341 IUPHAR:1909 PubChem Compound:3715 DrugBank:DB00328 CiteXplore:22931205 National Drug Code Directory:42211-101-11 ChEBI:5918 RxList:http://www.rxlist.com/cgi/generic/indometh.htm Drugs Product Database (DPD):2143372 Wikipedia:Indometacin ChemSpider:3584 PubChem Substance:46508291 CiteXplore:5952296 CASRN:53-86-1 Patent:US3161654 NIST Chemistry WebBook:53-86-1 BindingDB:17638 Guide To Pharmacology:1909 KEGG COMPOUND:C01926
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