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The Drug-Drug Interactions Ontology
| Preferred Name | ethosuximide | |
| Synonyms |
Ethosuximide etosuximida 3-ethyl-3-methylsuccinimide 3-methyl-3-ethylpyrrolidine-2,5-dione 2-ethyl-2-methylsuccinimide Aethosuximide ethosuximidum gamma-methyl-gamma-ethyl-succinimide gamma-ethyl-gamma-methyl-succinimide (+-)-2-ethyl-2-methylsuccinimide alpha-methyl-alpha-ethylsuccinimide 3-methyl-3-ethylsuccinimide ethosuximide 2-methyl-2-ethylsuccinimide alpha-ethyl-alpha-methylsuccinimide 3-ethyl-3-methyl-2,5-pyrrolidinedione C7H11NO2 3-ethyl-3-methylpyrrolidine-2,5-dione |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_4887 |
|
| AHFScode |
28:12.20
|
|
| altId |
CHEBI:131811
|
|
| ATCCode |
N03AD01
|
|
| binds |
http://purl.obolibrary.org/obo/dinto_0023 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_0456 http://purl.obolibrary.org/obo/dinto_0293 |
|
| CASRN |
77-67-8
|
|
| DBBrand |
suxilep atysmal pyknolepsinum zarondan piknolepsin succimal etomal suxinutin zarontin succimitin ethymal petinimid thetamid petnidan mesentol thilopemal asamid peptinimid pentinimid suximal capitus pemalin epileo petit mal ronton zarodan simatin zartalin emeside zaraondan pemal suxin
|
|
| DBname |
ethosuximide
|
|
| DBSynonym |
etosuximida ethosuxide ethosuccinimide ethosuccimide aethosuximide
|
|
| Definition |
Pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.
|
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0000267 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0001105 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0001336 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000362 |
|
| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)
|
|
| InChIKey |
InChIKey=HAPOVYFOVVWLRS-UHFFFAOYSA-N
|
|
| inhibits | ||
| is metabolised by |
http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_0456 http://purl.obolibrary.org/obo/dinto_0293 |
|
| is substrate of |
http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_0456 http://purl.obolibrary.org/obo/dinto_0293 |
|
| label |
ethosuximide
|
|
| may interact with |
http://purl.obolibrary.org/obo/dinto_DB00582 |
|
| prefixIRI |
obo2:CHEBI_4887
|
|
| prefLabel |
ethosuximide
|
|
| SMILES |
CCC1(C)CC(=O)NC1=O
|
|
| Synonym |
Ethosuximide etosuximida 3-ethyl-3-methylsuccinimide 3-methyl-3-ethylpyrrolidine-2,5-dione 2-ethyl-2-methylsuccinimide Aethosuximide ethosuximidum gamma-methyl-gamma-ethyl-succinimide gamma-ethyl-gamma-methyl-succinimide (+-)-2-ethyl-2-methylsuccinimide alpha-methyl-alpha-ethylsuccinimide 3-methyl-3-ethylsuccinimide ethosuximide 2-methyl-2-ethylsuccinimide alpha-ethyl-alpha-methylsuccinimide 3-ethyl-3-methyl-2,5-pyrrolidinedione C7H11NO2 3-ethyl-3-methylpyrrolidine-2,5-dione
|
|
| xref |
ChEMBL:8246220 ChEMBL:17481896 CiteXplore:21945797 NIST Chemistry WebBook:77-67-8 CiteXplore:21332949 ChEMBL:1992141 ChemSpider:3175 DrugBank:DB00593 RxList:http://www.rxlist.com/cgi/generic/ethosuximide.htm PubChem Substance:46507617 KEGG COMPOUND:C07505 Wikipedia:Ethosuximide ChEMBL:3336019 Reaxys:117054 ChEMBL:2296016 Drugs.com:http://www.drugs.com/cdi/ethosuximide.html Wikipedia:http://en.wikipedia.org/wiki/Ethosuximide ChEMBL:1681105 ChEMBL:17011080 CiteXplore:19005061 Drugs Product Database (DPD):23485 KEGG DRUG:D00539 ChEMBL:17046248 ChEMBL:1847429 National Drug Code Directory:0071-0237-24 BindingDB:50240424 PharmGKB:PA449533 ChEMBL:9016327 ChEMBL:8691481 ChEMBL:8627613 PubChem Compound:3291 ChEBI:4887 ChEMBL:2061925 ChEMBL:3820228 ChEMBL:17451232 CASRN:77-67-8 ChEMBL:2308142 ChEMBL:12873507
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| subClassOf |
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