| Synonyms |
clarithromycin
6-O-methylerythromycin
CLARITHROMYCIN
O(6)-methylerythromycin
clarithromycine
clarithromycinum
6-O-methylerythromycin A
CLA
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
clarithromycina
Clarithromycin
C38H69NO13
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| Definition |
The 6-O-methyl ether of erythromycin A, clarithromycin is a macrolide antibiotic used in the treatment of respiratory-tract, skin and soft-tissue infections. It is also used to eradicate Helicobacter pylori in the treatment of peptic ulcer disease. It prevents bacteria from growing by interfering with their protein synthesis.
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| InChI |
InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
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| Synonym |
clarithromycin 6-O-methylerythromycin CLARITHROMYCIN O(6)-methylerythromycin clarithromycine clarithromycinum 6-O-methylerythromycin A CLA (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione clarithromycina Clarithromycin C38H69NO13
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| xref |
RxList:http://www.rxlist.com/cgi/generic/clarith.htm National Drug Code Directory:0378-8250-91 Drugs Product Database (DPD):2244756 PDBeChem:CTY KEGG COMPOUND:C06912 Drugs.com:http://www.drugs.com/clarithromycin.html ChEMBL:16387493 Patent:EP41355 Beilstein:3581974 DrugBank:DB01211 Patent:US4331803 Wikipedia:http://en.wikipedia.org/wiki/Clarithromycin KEGG DRUG:D00276 CASRN:81103-11-9 ChEBI:3732 LIPID MAPS:LMPK04000014 PharmGKB:PA449028
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