The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Preferred Name	amoxapine
Synonyms	amoxapina amoxapine 2-chloro-11-(piperazin-1-yl)dibenzo[b,f][1,4]oxazepine Desmethylloxapin amoxapinum 13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaene 2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine C17H16ClN3O
ID	http://purl.obolibrary.org/obo/CHEBI_2675
ATCCode	N06AA17
binds	http://purl.obolibrary.org/obo/dinto_2714 http://purl.obolibrary.org/obo/dinto_0068 http://purl.obolibrary.org/obo/dinto_3582 http://purl.obolibrary.org/obo/dinto_2875 http://purl.obolibrary.org/obo/dinto_3182 http://purl.obolibrary.org/obo/dinto_2804 http://purl.obolibrary.org/obo/dinto_0909 http://purl.obolibrary.org/obo/dinto_0234 http://purl.obolibrary.org/obo/dinto_1135 http://purl.obolibrary.org/obo/dinto_2993
blocks	http://purl.obolibrary.org/obo/dinto_2875 http://purl.obolibrary.org/obo/dinto_3182 http://purl.obolibrary.org/obo/dinto_2804 http://purl.obolibrary.org/obo/dinto_0909 http://purl.obolibrary.org/obo/dinto_0234 http://purl.obolibrary.org/obo/dinto_1135
CASRN	14028-44-5
DBBrand	demolox defanyl asendis ascendin moxadil
DBname	amoxapine
DBSynonym	amoxepine
Definition	A dibenzooxazepine compound having a chloro substituent at the 2-position and a piperazin-1-yl group at the 11-position.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000589 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000335 http://purl.obolibrary.org/obo/OAE_0000659 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0001069 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0001068 http://purl.obolibrary.org/obo/OAE_0000309 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000842 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000038 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000487 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001291 http://purl.obolibrary.org/obo/OAE_0000565 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000881 http://purl.obolibrary.org/obo/OAE_0001309 http://purl.obolibrary.org/obo/OAE_0000534 http://purl.obolibrary.org/obo/OAE_0000402
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2714
has role	http://purl.obolibrary.org/obo/CHEBI_50949 http://purl.obolibrary.org/obo/CHEBI_48561 http://purl.obolibrary.org/obo/CHEBI_35640 http://purl.obolibrary.org/obo/CHEBI_35469
InChI	InChI=1S/C17H16ClN3O/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2
InChIKey	InChIKey=QWGDMFLQWFTERH-UHFFFAOYSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_2714 http://purl.obolibrary.org/obo/dinto_0068
is metabolised by	http://purl.obolibrary.org/obo/dinto_2993
is substrate of	http://purl.obolibrary.org/obo/dinto_2993
label	amoxapine
may interact with	http://purl.obolibrary.org/obo/CHEBI_32250 http://purl.obolibrary.org/obo/CHEBI_102524 http://purl.obolibrary.org/obo/CHEBI_9943 http://purl.obolibrary.org/obo/CHEBI_2549 http://purl.obolibrary.org/obo/CHEBI_28918 http://purl.obolibrary.org/obo/CHEBI_8093 http://purl.obolibrary.org/obo/CHEBI_37924 http://purl.obolibrary.org/obo/CHEBI_4670 http://purl.obolibrary.org/obo/dinto_DB00723 http://purl.obolibrary.org/obo/CHEBI_156095 http://purl.obolibrary.org/obo/CHEBI_42944 http://purl.obolibrary.org/obo/dinto_DB00209 http://purl.obolibrary.org/obo/dinto_DB01364 http://purl.obolibrary.org/obo/dinto_DB01064 http://purl.obolibrary.org/obo/dinto_DB00857 http://purl.obolibrary.org/obo/CHEBI_8874 http://purl.obolibrary.org/obo/CHEBI_61049 http://purl.obolibrary.org/obo/dinto_DB00726 http://purl.obolibrary.org/obo/CHEBI_149226 http://purl.obolibrary.org/obo/CHEBI_53289 http://purl.obolibrary.org/obo/dinto_DB00342 http://purl.obolibrary.org/obo/dinto_DB01291 http://purl.obolibrary.org/obo/CHEBI_3699 http://purl.obolibrary.org/obo/CHEBI_51364 http://purl.obolibrary.org/obo/dinto_DB01366 http://purl.obolibrary.org/obo/CHEBI_6794 http://purl.obolibrary.org/obo/CHEBI_18243 http://purl.obolibrary.org/obo/dinto_DB00780 http://purl.obolibrary.org/obo/CHEBI_9449 http://purl.obolibrary.org/obo/CHEBI_9654 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/dinto_DB00237 http://purl.obolibrary.org/obo/dinto_DB00427 http://purl.obolibrary.org/obo/dinto_DB00365 http://purl.obolibrary.org/obo/CHEBI_10119 http://purl.obolibrary.org/obo/CHEBI_5138 http://purl.obolibrary.org/obo/CHEBI_9635 http://purl.obolibrary.org/obo/CHEBI_51209 http://purl.obolibrary.org/obo/CHEBI_3720 http://purl.obolibrary.org/obo/dinto_DB01363 http://purl.obolibrary.org/obo/dinto_DB00397 http://purl.obolibrary.org/obo/CHEBI_27796 http://purl.obolibrary.org/obo/CHEBI_45367 http://purl.obolibrary.org/obo/dinto_DB01247 http://purl.obolibrary.org/obo/dinto_DB00752 http://purl.obolibrary.org/obo/CHEBI_45716 http://purl.obolibrary.org/obo/dinto_DB00382 http://purl.obolibrary.org/obo/dinto_DB01171 http://purl.obolibrary.org/obo/CHEBI_5557 http://purl.obolibrary.org/obo/dinto_DB01365 http://purl.obolibrary.org/obo/dinto_DB01105 http://purl.obolibrary.org/obo/dinto_DB00488 http://purl.obolibrary.org/obo/CHEBI_63620 http://purl.obolibrary.org/obo/dinto_DB00503 http://purl.obolibrary.org/obo/CHEBI_18357 http://purl.obolibrary.org/obo/CHEBI_10124 http://purl.obolibrary.org/obo/CHEBI_46631 http://purl.obolibrary.org/obo/CHEBI_28077 http://purl.obolibrary.org/obo/CHEBI_195280 http://purl.obolibrary.org/obo/dinto_DB00816 http://purl.obolibrary.org/obo/dinto_DB01208 http://purl.obolibrary.org/obo/dinto_DB01623 http://purl.obolibrary.org/obo/CHEBI_5118 http://purl.obolibrary.org/obo/dinto_DB06700
modulates	http://purl.obolibrary.org/obo/dinto_2875 http://purl.obolibrary.org/obo/dinto_3182 http://purl.obolibrary.org/obo/dinto_2804 http://purl.obolibrary.org/obo/dinto_0909 http://purl.obolibrary.org/obo/dinto_0234 http://purl.obolibrary.org/obo/dinto_1135
prefixIRI	obo2:CHEBI_2675
prefLabel	amoxapine
related with	http://purl.obolibrary.org/obo/dinto_3582
SMILES	Clc1ccc2Oc3ccccc3N=C(N3CCNCC3)c2c1 ClC1=CC2=C(OC3=CC=CC=C3N=C2N2CCNCC2)C=C1
Synonym	amoxapina amoxapine 2-chloro-11-(piperazin-1-yl)dibenzo[b,f][1,4]oxazepine Desmethylloxapin amoxapinum 13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaene 2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine C17H16ClN3O
xref	ChemSpider:2085 KEGG DRUG:D00228 DrugBank:DB00543 PubChem Substance:46509117 Patent:US3663696 Beilstein:832057 National Drug Code Directory:0591-5713-01 BindingDB:22870 Wikipedia:Amoxapine NIST Chemistry WebBook:14028-44-5 Guide To Pharmacology:201 RxList:http://www.rxlist.com/cgi/generic/amoxapine.htm PharmGKB:PA448405 Drugs.com:http://www.drugs.com/cdi/amoxapine.html Wikipedia:http://en.wikipedia.org/wiki/Amoxapine Drugs Product Database (DPD):527106 Patent:FR1508536 DrugBank:14028-44-5 IUPHAR:201 PubChem Compound:2170 ChEBI:2675 CASRN:14028-44-5 ChEMBL:255045
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_2675	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2675	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2675	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2675	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2675	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2675	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2675	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_2675	CHEBI	LOOM
http://purl.bioontology.org/ontology/LNC/LP16032-2	LOINC	LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClassf7b908ea_38ea_445c_884d_fe769a0913d0	WWECA	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373754002	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146270	NDFRT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.494.347.500.040	RH-MESH	LOOM
http://purl.obolibrary.org/obo/MESH_D000657	BERO	LOOM
http://purl.obolibrary.org/obo/OMIT_0002072	OMIT	LOOM
http://purl.bioontology.org/ontology/RCD/d7h..	RCD	LOOM
http://purl.jp/bio/4/id/200906094190453228	IOBC	LOOM
http://purl.bioontology.org/ontology/RXNORM/722	RXNORM	LOOM
http://purl.bioontology.org/ontology/NDDF/001506	NDDF	LOOM
http://www.co-ode.org/ontologies/galen#Amoxapine	GALEN	LOOM
http://purl.obolibrary.org/obo/NCIT_C47397	BERO	LOOM
http://purl.bioontology.org/ontology/ATC/N06AA17	ATC	LOOM
http://www.drugbank.ca/drugs/DB00543	FTC	LOOM
http://purl.bioontology.org/ontology/MESH/D000657	MESH	LOOM
http://www.case.edu/EpilepsyOntology.owl#Amoxapine	EPSO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017973	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/VANDF/4017919	VANDF	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004909	LOINC	LOOM
http://purl.bioontology.org/ontology/SNMI/C-62260	SNMI	LOOM
http://www.case.edu/EpSO.owl#Amoxapine	MEPO	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47397	NCIT	LOOM
http://stirdf.jst.go.jp/id/200907078036359322	IOBC	LOOM
https://go.drugbank.com/drugs/DB00543	MDM	LOOM
http://purl.obolibrary.org/obo/CHEBI_2675	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_2675	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_2675	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_2675	BIOMODELS	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D000657	RH-MESH	LOOM