loading...| Preferred Name | L-thyroxine | |
| Synonyms |
C15H11I4NO4 3,5,3',5'-tetraiodo-L-thyronine 4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-L-phenylalanine L-T4 3,5,3',5'-TETRAIODO-L-THYRONINE 3,3',5,5'-tetraiodo-L-thyronine (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid L-Thyroxine levothyroxine Levothyroxin T4 O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine L-thyroxine |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_18332 |
|
| activates | ||
| AHFScode |
68:36.04 |
|
| altId |
CHEBI:45848 CHEBI:13177 CHEBI:7663 CHEBI:21406 |
|
| ATCCode |
H03AA01 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_2915 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_1573 http://purl.obolibrary.org/obo/dinto_1805 http://purl.obolibrary.org/obo/dinto_2129 http://purl.obolibrary.org/obo/dinto_2019 http://purl.obolibrary.org/obo/dinto_1815 http://purl.obolibrary.org/obo/dinto_1824 http://purl.obolibrary.org/obo/dinto_1987 http://purl.obolibrary.org/obo/dinto_0505 http://purl.obolibrary.org/obo/dinto_0217 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_3533 http://purl.obolibrary.org/obo/dinto_1129 |
|
| CASRN |
51-48-9 |
|
| DBBrand |
levolet thyratabs thyroxin thyroxinal synthroid levothyrox thyroxevan letter synthroid sodium thyreoideum levothroid unithroid oroxine novothyrox thyro-tabs eltroxin levoxyl laevoxin levaxin euthyrox thyrax |
|
| DBname |
levothyroxine |
|
| DBSynonym |
thx laevothyroxinum thyroxine iodine (-)-thyroxine levothyroxine sodium levothyroxin t4 levothyroxine o-(4-hydroxy-3,5-diidophenyl)-3,5-diiodo-l-tyrosine l-thryoxin tetraiodothyronine l-thyroxine 3,3',5,5'-tetraiodo-l-thyronine levo-t |
|
| Definition |
The L-enantiomer of thyroxine. |
|
| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1 |
|
| InChIKey |
InChIKey=XUIIKFGFIJCVMT-LBPRGKRZSA-N |
|
| induces | ||
| inhibits | ||
| is metabolised by | ||
| is substrate of | ||
| is transported by | ||
| label |
L-thyroxine |
|
| may interact with |
http://purl.obolibrary.org/obo/CHEBI_4551 http://purl.obolibrary.org/obo/dinto_DB00893 http://purl.obolibrary.org/obo/CHEBI_53766 http://purl.obolibrary.org/obo/CHEBI_8772 http://purl.obolibrary.org/obo/dinto_DB00258 http://purl.obolibrary.org/obo/CHEBI_133809 http://purl.obolibrary.org/obo/dinto_DB00364 http://purl.obolibrary.org/obo/CHEBI_10033 http://purl.obolibrary.org/obo/dinto_DB01164 http://purl.obolibrary.org/obo/CHEBI_4513 http://purl.obolibrary.org/obo/dinto_DB01373 http://purl.obolibrary.org/obo/CHEBI_59602 |
|
| modulates | ||
| prefixIRI |
obo2:CHEBI_18332 |
|
| prefLabel |
L-thyroxine |
|
| related with |
http://purl.obolibrary.org/obo/dinto_1573 http://purl.obolibrary.org/obo/dinto_1805 http://purl.obolibrary.org/obo/dinto_2129 http://purl.obolibrary.org/obo/dinto_2019 http://purl.obolibrary.org/obo/dinto_1815 http://purl.obolibrary.org/obo/dinto_1824 http://purl.obolibrary.org/obo/dinto_1987 |
|
| SMILES |
N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O)=O N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O |
|
| Synonym |
C15H11I4NO4 3,5,3',5'-tetraiodo-L-thyronine 4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-L-phenylalanine L-T4 3,5,3',5'-TETRAIODO-L-THYRONINE 3,3',5,5'-tetraiodo-L-thyronine (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid L-Thyroxine levothyroxine Levothyroxin T4 O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine L-thyroxine |
|
| xref |
Drugs.com:http://www.drugs.com/levothyroxine.html DrugBank:DB00451 PDBeChem:T44 Wikipedia:http://en.wikipedia.org/wiki/Levothyroxine PubChem Compound:5819 PubChem Substance:46507672 RxList:http://www.rxlist.com/cgi/generic/levothy.htm Beilstein:7002831 KEGG COMPOUND:C01829 CiteXplore:15206581 ChemSpider:5614 CASRN:51-48-9 ChEMBL:569690 Drugs Product Database (DPD):2245948 Wikipedia:Levothyroxine National Drug Code Directory:0781-5180-01 Guide To Pharmacology:2635 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/syn1421.shtml IUPHAR:2635 ChEBI:18332 Beilstein:2228515 PharmGKB:PA450221 |
|
| subClassOf |