The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

L-dopa
Synonyms

(-)-dopa

Dopar

3,4-DIHYDROXYPHENYLALANINE

beta-(3,4-dihydroxyphenyl)alanine

L-dopa

levodopum

L-Dopa

C9H11NO4

L-beta-(3,4-Dihydroxyphenyl)alanine

beta-(3,4-dihydroxyphenyl)-L-alanine

L-DOPA

Dihydroxy-L-phenylalanine

3-Hydroxy-L-tyrosine

(2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid

3,4-Dihydroxy-L-phenylalanine

(-)-3-(3,4-dihydroxyphenyl)-L-alanine

levodopa

ID

http://purl.obolibrary.org/obo/CHEBI_15765

activates

http://purl.obolibrary.org/obo/dinto_2804

http://purl.obolibrary.org/obo/dinto_4010

http://purl.obolibrary.org/obo/dinto_0656

http://purl.obolibrary.org/obo/dinto_0909

http://purl.obolibrary.org/obo/dinto_2705

altId

CHEBI:49933

CHEBI:11693

CHEBI:41871

CHEBI:1377

CHEBI:19825

CHEBI:13098

CHEBI:75987

ATCCode

N04BA01

N04BA04

binds

http://purl.obolibrary.org/obo/dinto_1803

http://purl.obolibrary.org/obo/dinto_2004

http://purl.obolibrary.org/obo/dinto_2833

http://purl.obolibrary.org/obo/dinto_3400

http://purl.obolibrary.org/obo/dinto_2129

http://purl.obolibrary.org/obo/dinto_2804

http://purl.obolibrary.org/obo/dinto_4010

http://purl.obolibrary.org/obo/dinto_0656

http://purl.obolibrary.org/obo/dinto_0909

http://purl.obolibrary.org/obo/dinto_2705

http://purl.obolibrary.org/obo/dinto_2993

CASRN

59-92-7

DBBrand

dopasol

pardopa

veldopa

cidandopa

dopaflex

dopar

doprin

dopalina

brocadopa

syndopa

prodopa

laradopa

dopaidan

bendopa

dopastral

dopaston

levedopa

eurodopa

helfo-dopa

levopa

eldopar

larodopa

ledopa

deadopa

dopal-fher

weldopa

eldopal

insulamina

eldopatec

doparl

parda

maipedopa

dopal

doparkine

DBname

levodopa

DBSynonym

dopa

l-dihydroxyphenylalanine

l-dopa

3,4-dihydroxyphenylalanine

Definition

An optically active form of dopa having L-configuration. Used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2804

http://purl.obolibrary.org/obo/dinto_4010

http://purl.obolibrary.org/obo/dinto_0656

http://purl.obolibrary.org/obo/dinto_0909

http://purl.obolibrary.org/obo/dinto_2705

has role

http://purl.obolibrary.org/obo/CHEBI_48560

http://purl.obolibrary.org/obo/CHEBI_66956

http://purl.obolibrary.org/obo/CHEBI_59174

http://purl.obolibrary.org/obo/CHEBI_50910

http://purl.obolibrary.org/obo/CHEBI_62215

http://purl.obolibrary.org/obo/CHEBI_35219

http://purl.obolibrary.org/obo/CHEBI_50266

http://purl.obolibrary.org/obo/CHEBI_48407

InChI

InChI=1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1

InChIKey

InChIKey=WTDRDQBEARUVNC-LURJTMIESA-N

inhibits

http://purl.obolibrary.org/obo/dinto_1803

http://purl.obolibrary.org/obo/dinto_2004

is metabolised by

http://purl.obolibrary.org/obo/dinto_2993

is substrate of

http://purl.obolibrary.org/obo/dinto_2993

label

L-dopa

may interact with

http://purl.obolibrary.org/obo/CHEBI_8107

http://purl.obolibrary.org/obo/dinto_DB00893

http://purl.obolibrary.org/obo/dinto_DB01267

http://purl.obolibrary.org/obo/CHEBI_51364

http://purl.obolibrary.org/obo/dinto_DB00780

http://purl.obolibrary.org/obo/CHEBI_10119

http://purl.obolibrary.org/obo/dinto_DB01247

http://purl.obolibrary.org/obo/CHEBI_9467

http://purl.obolibrary.org/obo/dinto_DB00752

http://purl.obolibrary.org/obo/CHEBI_61058

http://purl.obolibrary.org/obo/CHEBI_107736

http://purl.obolibrary.org/obo/dinto_DB01320

http://purl.obolibrary.org/obo/dinto_DB01623

modulates

http://purl.obolibrary.org/obo/dinto_2804

http://purl.obolibrary.org/obo/dinto_4010

http://purl.obolibrary.org/obo/dinto_0656

http://purl.obolibrary.org/obo/dinto_0909

http://purl.obolibrary.org/obo/dinto_2705

prefixIRI

obo2:CHEBI_15765

prefLabel

L-dopa

related with

http://purl.obolibrary.org/obo/dinto_2833

http://purl.obolibrary.org/obo/dinto_3400

http://purl.obolibrary.org/obo/dinto_2129

SMILES

N[C@@H](CC1=CC(O)=C(O)C=C1)C(O)=O

N[C@@H](Cc1ccc(O)c(O)c1)C(O)=O

Synonym

(-)-dopa

Dopar

3,4-DIHYDROXYPHENYLALANINE

beta-(3,4-dihydroxyphenyl)alanine

L-dopa

levodopum

L-Dopa

C9H11NO4

L-beta-(3,4-Dihydroxyphenyl)alanine

beta-(3,4-dihydroxyphenyl)-L-alanine

L-DOPA

Dihydroxy-L-phenylalanine

3-Hydroxy-L-tyrosine

(2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid

3,4-Dihydroxy-L-phenylalanine

(-)-3-(3,4-dihydroxyphenyl)-L-alanine

levodopa

xref

CiteXplore:22592937

Reaxys:2215169

CiteXplore:23389938

CiteXplore:23127496

PubChem Compound:6047

Drugs.com:http://www.drugs.com/mtm/levodopa.html

Guide To Pharmacology:3639

ChEMBL:212655

IUPHAR:3639

Beilstein:6060047

PDBeChem:DAH_LFOH

PDB:DAH

CiteXplore:22491024

COMe:MOL000169

NIST Chemistry WebBook:59-92-7

CiteXplore:18690870

Beilstein:2215169

CiteXplore:23389842

CiteXplore:23211937

HMDB:HMDB00181

CiteXplore:8301021

Wikipedia:Levodopa

DrugBank:DB01235

Gmelin:365846

MetaCyc:L-DIHYDROXY-PHENYLALANINE

KEGG COMPOUND:C00355

PharmGKB:PA450213

KEGG DRUG:D00059

ChemSpider:5824

CiteXplore:23357114

ChEBI:15765

CiteXplore:23206800

CiteXplore:23390548

Wikipedia:http://en.wikipedia.org/wiki/Levodopa

PubChem Substance:46508120

RxList:http://www.rxlist.com/cgi/generic3/stalevo.htm

CASRN:59-92-7

CiteXplore:23038403

CiteXplore:23196068

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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http://purl.obolibrary.org/obo/CHEBI_15765 OBA SAME_URI
http://purl.obolibrary.org/obo/CHEBI_15765 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_15765 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_15765 EUPATH SAME_URI
http://purl.obolibrary.org/obo/CHEBI_15765 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_15765 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_15765 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_15765 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_15765 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_15765 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_15765 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_15765 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CHEBI_15765 ECTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_15765 HINO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_15765 ODNAE SAME_URI
http://purl.obolibrary.org/obo/CHEBI_15765 OBA LOOM
rgo:03655 GAMUTS LOOM
http://purl.bioontology.org/ontology/LNC/LP32555-2 LOINC LOOM
http://stirdf.jst.go.jp/id/200907032063684472 IOBC LOOM
http://purl.obolibrary.org/obo/CHEBI_15765 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_15765 EUPATH LOOM
http://purl.obolibrary.org/obo/CHEBI_15765 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_15765 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_15765 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_15765 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_15765 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_15765 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_15765 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_15765 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_15765 ECTO LOOM
http://purl.obolibrary.org/obo/CHEBI_15765 HINO LOOM
http://purl.obolibrary.org/obo/UPa_UPC00355 UPA LOOM
http://purl.jp/bio/4/id/200906090903834205 IOBC LOOM
http://purl.obolibrary.org/obo/IMR_0200290 HOIP LOOM
http://purl.obolibrary.org/obo/IMR_0200290 TXPO LOOM