loading...| Preferred Name | all-trans-retinoic acid | |
| Synonyms |
all-(E)-Retinoic acid all-trans-Tretinoin (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid Tretin M Acide retinoique (French) (DSL) 3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid Vesanoid all-trans-Retinoic acid Retisol-A C20H28O2 all-trans-beta-Retinoic acid Tretinoine (French) (EINECS) 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ECL) Retinoic acid RETINOIC ACID (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid all-trans-Vitamin A1 acid beta-Retinoic acid AGN 100335 Renova Retin-A Ro 1-5488 all-trans-Vitamin A acid Stieva-A trans-Retinoic acid Vitamin A acid tretinoin |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_15367 |
|
| activates |
http://purl.obolibrary.org/obo/dinto_3341 http://purl.obolibrary.org/obo/dinto_1077 |
|
| AHFScode |
92:00.00 84:16.00 |
|
| altId |
CHEBI:8815 CHEBI:45376 |
|
| ATCCode |
D10AD04 D10BA01 L01XX22 L01XX14 D10AD01 D10AD51 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_0255 http://purl.obolibrary.org/obo/dinto_3881 http://purl.obolibrary.org/obo/dinto_3485 http://purl.obolibrary.org/obo/dinto_0955 http://purl.obolibrary.org/obo/dinto_1077 http://purl.obolibrary.org/obo/dinto_2703 http://purl.obolibrary.org/obo/dinto_3482 http://purl.obolibrary.org/obo/dinto_3341 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_0762 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_2496 http://purl.obolibrary.org/obo/dinto_1956 http://purl.obolibrary.org/obo/dinto_1959 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_0465 |
|
| CASRN |
302-79-4 |
|
| DBBrand |
claravis accutane aberel aknoten airol solage lsotretinoin atra-iv retisol-a amnesteem aknefug dermairol eudyna stieva-a sotret vitinoin stieva-a forte |
|
| DBname |
tretinoin |
|
| DBSynonym |
beta-retinoic acid all trans-retinoic acid retionic acid atra all trans retinoic acid |
|
| Definition |
A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry. |
|
| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_1077 |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_22586 http://purl.obolibrary.org/obo/CHEBI_50176 http://purl.obolibrary.org/obo/CHEBI_62488 http://purl.obolibrary.org/obo/CHEBI_63794 http://purl.obolibrary.org/obo/CHEBI_67079 |
|
| InChI |
InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+ |
|
| InChIKey |
InChIKey=SHGAZHPCJJPHSC-YCNIQYBTSA-N |
|
| is metabolised by |
http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_0762 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_2496 http://purl.obolibrary.org/obo/dinto_1956 http://purl.obolibrary.org/obo/dinto_1959 |
|
| is substrate of |
http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_0762 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_2496 http://purl.obolibrary.org/obo/dinto_1956 http://purl.obolibrary.org/obo/dinto_1959 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_0465 |
|
| is transported by | ||
| label |
all-trans-retinoic acid |
|
| may interact with |
http://purl.obolibrary.org/obo/CHEBI_7627 http://purl.obolibrary.org/obo/CHEBI_585948 http://purl.obolibrary.org/obo/CHEBI_5296 http://purl.obolibrary.org/obo/CHEBI_8107 http://purl.obolibrary.org/obo/CHEBI_41774 http://purl.obolibrary.org/obo/dinto_DB00794 http://purl.obolibrary.org/obo/CHEBI_37924 http://purl.obolibrary.org/obo/dinto_DB00108 http://purl.obolibrary.org/obo/CHEBI_149836 http://purl.obolibrary.org/obo/CHEBI_5959 http://purl.obolibrary.org/obo/CHEBI_6541 http://purl.obolibrary.org/obo/CHEBI_45304 http://purl.obolibrary.org/obo/CHEBI_50838 http://purl.obolibrary.org/obo/CHEBI_8069 http://purl.obolibrary.org/obo/CHEBI_49603 http://purl.obolibrary.org/obo/CHEBI_41423 http://purl.obolibrary.org/obo/CHEBI_50845 http://purl.obolibrary.org/obo/dinto_DB01357 http://purl.obolibrary.org/obo/CHEBI_27701 http://purl.obolibrary.org/obo/CHEBI_8228 http://purl.obolibrary.org/obo/dinto_DB00162 http://purl.obolibrary.org/obo/CHEBI_31580 http://purl.obolibrary.org/obo/CHEBI_8768 http://purl.obolibrary.org/obo/CHEBI_52172 http://purl.obolibrary.org/obo/CHEBI_3387 http://purl.obolibrary.org/obo/CHEBI_50815 http://purl.obolibrary.org/obo/CHEBI_50924 http://purl.obolibrary.org/obo/dinto_DB00440 http://purl.obolibrary.org/obo/CHEBI_50122 http://purl.obolibrary.org/obo/CHEBI_27902 http://purl.obolibrary.org/obo/CHEBI_50777 http://purl.obolibrary.org/obo/dinto_DB00977 http://purl.obolibrary.org/obo/CHEBI_6443 http://purl.obolibrary.org/obo/dinto_DB00072 http://purl.obolibrary.org/obo/dinto_DB00503 http://purl.obolibrary.org/obo/dinto_DB01320 http://purl.obolibrary.org/obo/CHEBI_15854 http://purl.obolibrary.org/obo/CHEBI_4453 http://purl.obolibrary.org/obo/CHEBI_28077 http://purl.obolibrary.org/obo/CHEBI_50694 http://purl.obolibrary.org/obo/dinto_DB06210 |
|
| modulates |
http://purl.obolibrary.org/obo/dinto_3341 http://purl.obolibrary.org/obo/dinto_1077 |
|
| prefixIRI |
obo2:CHEBI_15367 |
|
| prefLabel |
all-trans-retinoic acid |
|
| related with |
http://purl.obolibrary.org/obo/dinto_0255 http://purl.obolibrary.org/obo/dinto_3881 |
|
| SMILES |
CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O CC(\\C=C\\C1=C(C)CCCC1(C)C)=C/C=C/C(C)=C/C(O)=O |
|
| Synonym |
all-(E)-Retinoic acid all-trans-Tretinoin (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid Tretin M Acide retinoique (French) (DSL) 3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid Vesanoid all-trans-Retinoic acid Retisol-A C20H28O2 all-trans-beta-Retinoic acid Tretinoine (French) (EINECS) 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ECL) Retinoic acid RETINOIC ACID (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid all-trans-Vitamin A1 acid beta-Retinoic acid AGN 100335 Renova Retin-A Ro 1-5488 all-trans-Vitamin A acid Stieva-A trans-Retinoic acid Vitamin A acid tretinoin |
|
| xref |
Wikipedia:http://en.wikipedia.org/wiki/Tretinoin CiteXplore:22180426 CiteXplore:15537748 PharmGKB:PA451746 CiteXplore:19597529 Beilstein:2057223 CiteXplore:15839997 CiteXplore:19427305 CiteXplore:18085670 CiteXplore:22244299 CiteXplore:16685080 CiteXplore:22514600 CiteXplore:22534100 CiteXplore:22538278 PubChem Substance:46504843 CiteXplore:19841174 CiteXplore:16920920 KEGG COMPOUND:C00777 CiteXplore:14704332 CiteXplore:18819820 CiteXplore:14581379 CiteXplore:15359008 CiteXplore:11556813 CiteXplore:11437362 CiteXplore:16720557 CiteXplore:22177959 CiteXplore:22134377 CiteXplore:18977311 DrugBank:DB00755 CiteXplore:11214352 CiteXplore:11343416 CiteXplore:14705145 CiteXplore:19587328 CiteXplore:15476854 CiteXplore:18400206 PDBeChem:REA CiteXplore:22532966 CiteXplore:15327395 CiteXplore:18678272 Wikipedia:Tretinoin CiteXplore:22428994 ChEBI:15367 ChemSpider:5337 CiteXplore:16847436 CiteXplore:15675886 CiteXplore:16819260 CiteXplore:18318655 CiteXplore:18052213 CiteXplore:17204142 CiteXplore:21924320 CiteXplore:18440196 CiteXplore:14627725 CiteXplore:15194426 CiteXplore:15318809 PubChem Compound:444795 CiteXplore:18322276 RxList:http://www.rxlist.com/cgi/generic/tretinoin.htm CiteXplore:16569247 CiteXplore:11896294 CiteXplore:17166212 CiteXplore:22261335 CiteXplore:11332619 CiteXplore:11073974 CiteXplore:16688769 CiteXplore:17073551 CiteXplore:14978018 CiteXplore:18162363 CiteXplore:18183617 CiteXplore:19814868 CiteXplore:14605492 CiteXplore:11722649 KEGG DRUG:D00094 LIPID MAPS:LMPR01090019 CiteXplore:11904404 ChEMBL:102208 CiteXplore:19144697 CiteXplore:22741806 CiteXplore:21898109 CASRN:302-79-4 HMDB:HMDB01852 Drugs.com:http://www.drugs.com/cdi/tretinoin.html CiteXplore:21993673 Drugs Product Database (DPD):2243914 Reaxys:2057223 CiteXplore:18404486 CiteXplore:19112091 CiteXplore:15539337 National Drug Code Directory:0062-0187-02 CiteXplore:15376324 |
|
| subClassOf |