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STO
Last uploaded:
November 28, 2017
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| Preferred Name | Warfarin | |
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| ID |
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_e4a06e5e_bdd1_49fc_814a_47a41d12ec58 |
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Warfarin, a coumarin derivative, produces an anticoagulant effect by interfering with the cyclic interconversion of vitamin K and its 2,3 epoxide (vitamin K epoxide). Vitamin K is a cofactor for the carboxylation of glutamate residues to γ-carboxyglutamates (Gla) on the N-terminal regions of vitamin K–dependent proteins .
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| label |
Warfarin
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| prefixIRI |
OWLClass_e4a06e5e_bdd1_49fc_814a_47a41d12ec58
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| prefLabel |
Warfarin
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| references |
Hirsh, J., Fuster, V., Ansell, J., & Halperin, J. L. (2003). American Heart Association/American College of Cardiology Foundation guide to warfarin therapy1. Journal of the American College of Cardiology, 41(9), 1633-1652.
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| synonyms |
Coumadin Panwarfin Sofarin
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| subClassOf |
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_b1f6b40e_dbaa_44e7_a0c2_d45e96672923 |
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