Preferred Name |
Nodular Lymphocyte Predominant Hodgkin Lymphoma |
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Synonyms |
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ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Nodular_Lymphocyte_Predominant_Hodgkin_s_Lymphoma |
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DEFINITION |
A monoclonal B-cell neoplasm characterized by a nodular, or a nodular and diffuse, polymorphous proliferation of scattered large neoplastic cells known as popcorn or L&H cells; the L&H cells are CD15 negative, and rarely positive for CD30 antigen. Patients are predominantly male, frequently in the 30-50 year age group. Most patients present with limited stage disease (localized peripheral lymphadenopathy, stage I or II); the prognosis of patients with stage I and stage II disease is very good. Advanced stages have an unfavorable prognosis. |
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FULL_SYN |
nodular lymphocyte-predominant Hodgkin lymphoma Nodular Lymphocyte Predominant Hodgkin's Lymphoma NLPHL |
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isDefinedBy |
A monoclonal B-cell neoplasm characterized by a nodular, or a nodular and diffuse, polymorphous proliferation of scattered large neoplastic cells known as popcorn or L&H cells; the L&H cells are CD15 negative, and rarely positive for CD30 antigen. Patients are predominantly male, frequently in the 30-50 year age group. Most patients present with limited stage disease (localized peripheral lymphadenopathy, stage I or II); the prognosis of patients with stage I and stage II disease is very good. Advanced stages have an unfavorable prognosis. |
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label |
Nodular Lymphocyte Predominant Hodgkin Lymphoma |
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prefixIRI |
Thesaurus:Nodular_Lymphocyte_Predominant_Hodgkin_s_Lymphoma |
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prefLabel |
Nodular Lymphocyte Predominant Hodgkin Lymphoma |
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Synonym |
nodular lymphocyte-predominant Hodgkin lymphoma Nodular Lymphocyte Predominant Hodgkin's Lymphoma NLPHL |
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subClassOf |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Hodgkin_s_Lymphoma |