COVID-19 Ontology

Last uploaded: February 25, 2021
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Preferred Name

Oxidative Stress
Synonyms

oxidative stress

Oxidative Stress
Definitions

A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products. The damage to biological tissues is caused by superoxide and other free radicals generated by many factors, including exposure to alcohol, medications, trauma, cold, toxins, and radiation or by antimicrobial cellular immunity, metabolic abnormality, or "normal" aging; not synonymous with hypoxia or hyperoxia. Oxidative stress promotes a range of degenerative disorders, including cancer, diabetes, premature aging, Alzheimer's, and many others.
ID

http://purl.obolibrary.org/obo/NCIT_C17741
ALT_DEFINITION

A condition in which antioxidant levels are lower than normal. Antioxidant levels are usually measured in blood plasma.
alternative_term

oxidative stress

Oxidative Stress
code

C17741
definition

A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products. The damage to biological tissues is caused by superoxide and other free radicals generated by many factors, including exposure to alcohol, medications, trauma, cold, toxins, and radiation or by antimicrobial cellular immunity, metabolic abnormality, or "normal" aging; not synonymous with hypoxia or hyperoxia. Oxidative stress promotes a range of degenerative disorders, including cancer, diabetes, premature aging, Alzheimer's, and many others.
fromBEL

true
fromPubMed

true
imported from

http://purl.obolibrary.org/obo/ncit.owl
label

Oxidative Stress
Legacy_Concept_Name

Oxidative_Stress
oboInOwl:hasDbXRef

https://www.ncbi.nlm.nih.gov/pubmed/32221983
preferred label

Oxidative Stress
Preferred_Name

Oxidative Stress
prefixIRI

NCIT:C17741
prefLabel

Oxidative Stress
Semantic_Type

Phenomenon or Process
textual definition

A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products. The damage to biological tissues is caused by superoxide and other free radicals generated by many factors, including exposure to alcohol, medications, trauma, cold, toxins, and radiation or by antimicrobial cellular immunity, metabolic abnormality, or "normal" aging; not synonymous with hypoxia or hyperoxia. Oxidative stress promotes a range of degenerative disorders, including cancer, diabetes, premature aging, Alzheimer's, and many others.
UMLS_CUI

C0242606
subClassOf

http://purl.obolibrary.org/obo/OGMS_0000061
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http://purl.obolibrary.org/obo/NCIT_C17741 BERO SAME_URI
http://doe-generated-ontology.com/OntoAD#C0242606 ONTOAD LOOM
http://purl.obolibrary.org/obo/MP_0003674 BMONT LOOM
http://www.ebi.ac.uk/efo/EFO_1001905 EFO LOOM
http://purl.obolibrary.org/obo/MP_0003674 MP LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17741 NCIT LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Oxidative_Stress APANEUROCLUSTER LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Oxidative_Stress APAONTO LOOM
http://localhost/plosthes.2017-1#8168 PLOSTHES LOOM
http://scai.fraunhofer.de/AlzheimerOntology#Oxidative_stress ADMO LOOM
http://purl.obolibrary.org/obo/OMIT_0018596 OMIT LOOM
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571345044435365986 ACVD_ONTOLOGY LOOM
http://purl.obolibrary.org/obo/MESH_D018384 BERO LOOM
http://purl.obolibrary.org/obo/NCIT_C17741 BERO LOOM
http://www.pepathway.org/peo/1.2#Oxidative_stress PE-O LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#G03.495.710 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#24884 OCHV LOOM
http://purl.jp/bio/4/id/200906073187092411 IOBC LOOM
http://scai.fraunhofer.de/MSOntology#Oxidative_stress MSO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D018384 RH-MESH LOOM
http://scai.fraunhofer.de/CSEO#CSEO_00000887 CSEO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0696141 OCHV LOOM
http://purl.bioontology.org/ontology/MEDDRA/10080562 MEDDRA LOOM
http://purl.bioontology.org/ontology/CSP/4001-0099 CRISP LOOM
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Oxidative_stress PCAO LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:00852 MIO LOOM
http://scai.fraunhofer.de/MSOntology#oxidative_stress MSO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0242606 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/D018384 MESH LOOM
http://www.bootstrep.eu/ontology/GRO#OxidativeStress GRO LOOM
http://purl.obolibrary.org/obo/MP_0003674 DIAB LOOM
http://purl.obolibrary.org/obo/MP_0003674 UPHENO LOOM
http://purl.obolibrary.org/obo/MP_0003674 CHIRO LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_8072c05a_983b_43cd_bd16_d011475a8444 STO-DRAFT LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_8072c05a_983b_43cd_bd16_d011475a8444 CVAO LOOM
http://www.semanticweb.org/ADMO#oxidativeStress ADMO LOOM
http://purl.obolibrary.org/obo/TO_0002657 BERO LOOM
http://purl.obolibrary.org/obo/TO_0002657 PTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#G07.700.830.750 RH-MESH LOOM
http://purl.enanomapper.org/onto/ENM_0000037 ENM LOOM