COVID-19 Ontology

Last uploaded: February 25, 2021
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Preferred Name

disulfiram
Synonyms

N,N,N',N'-tetraethylthiuram disulfide

1,1'-dithiobis(N,N-diethylthioformamide)

bis(diethylthiocarbamoyl) disulfide

Tetraethylthiuram disulfide

tetraethylthiuram disulfide

tetraethylthiuram disulphide

tetraethylthioperoxydicarbonic diamide

Antabuse

1,1',1'',1'''-[disulfanediylbis(carbonothioylnitrilo)]tetraethane

Disulfiram
Definitions

An organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties.
ID

http://purl.obolibrary.org/obo/CHEBI_4659
alternative_term

1,1',1'',1'''-[disulfanediylbis(carbonothioylnitrilo)]tetraethane

Disulfiram
charge

0
database_cross_reference

DrugBank:DB00822

PMID:15709459

PMID:16880974

PMID:25777347

Wikipedia:Disulfiram

PMID:26517513

PMID:17667894

KEGG:D00131

Drug_Central:928

PMID:19720750

KEGG:C01692

PMID:26314552

PMID:26235918

PMID:16426571

PMID:8572926

PMID:10841824

PMID:25565438

PMID:26239994

PMID:25464072

PMID:17079463

PMID:14978246

PMID:25495604

PMID:21471244

PMID:26033731

PMID:16666414

PMID:16661923

CAS:97-77-8

PMID:17579916

PMID:25557293

PMID:25445071

PMID:25476326

PMID:26224731

PMID:26550292

PMID:11005259

PMID:18579431

PMID:24496638

PMID:19787200

PMID:25657800

Reaxys:1712560

LINCS:LSM-5467

PMID:25133664

HMDB:HMDB0014960

PMID:8442800

PMID:15325261

PMID:11716515

PMID:19782464
definition

An organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties.
formula

C10H20N2S4
fromPubMed

true
has_obo_namespace

chebi_ontology
has_related_synonym

N,N,N',N'-tetraethylthiuram disulfide

1,1'-dithiobis(N,N-diethylthioformamide)

bis(diethylthiocarbamoyl) disulfide

Tetraethylthiuram disulfide

tetraethylthiuram disulfide

tetraethylthiuram disulphide

tetraethylthioperoxydicarbonic diamide

Antabuse
id

CHEBI:4659
imported from

http://purl.obolibrary.org/obo/chebi.owl
in_subset

http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR
inchi

InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3
inchikey

AUZONCFQVSMFAP-UHFFFAOYSA-N
label

disulfiram
mass

296.544
monoisotopicmass

296.05093
notation

CHEBI:4659
oboInOwl:hasDbXRef

https://www.ncbi.nlm.nih.gov/pubmed/32147628
preferred label

disulfiram
prefLabel

disulfiram
smiles

S(SC(N(CC)CC)=S)C(N(CC)CC)=S
textual definition

An organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties.
subClassOf

http://purl.obolibrary.org/obo/CHEBI_23888
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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_4659 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4659 FIDEO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4659 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4659 HOIP SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4659 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4659 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4659 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4659 TXPO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4659 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4659 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4659 ECTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4659 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4659 ODNAE SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4659 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4659 DRON LOOM
http://purl.jp/bio/4/id/200906089580597545 IOBC LOOM
https://go.drugbank.com/drugs/DB00822 MDM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387212009 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/MESH/D004221 MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP16119-7 LOINC LOOM
http://purl.obolibrary.org/obo/dinto_DB00822 DINTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.081.251.869.220.250 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/000752 NDDF LOOM
http://purl.obolibrary.org/obo/MESH_D004221 BERO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C447 NCIT LOOM
http://purl.bioontology.org/ontology/SNMI/C-B70A0 SNMI LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146816 NDFRT LOOM
http://purl.bioontology.org/ontology/VANDF/4018494 VANDF LOOM
http://purl.bioontology.org/ontology/RXNORM/3554 RXNORM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0012772 OCHV LOOM
http://stirdf.jst.go.jp/id/200907076711602786 IOBC LOOM
http://purl.bioontology.org/ontology/CSP/2903-9805 CRISP LOOM
http://purl.obolibrary.org/obo/OMIT_0005482 OMIT LOOM
http://purl.bioontology.org/ontology/ATC/N07BB01 ATC LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Disulfiram APAONTO LOOM
http://www.drugbank.ca/drugs/DB00822 FTC LOOM
http://purl.obolibrary.org/obo/NCIT_C447 BERO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016352 PMAPP-PMO LOOM
http://www.co-ode.org/ontologies/galen#Disulfiram GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.706.200.200 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_4659 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_4659 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_4659 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_4659 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_4659 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4659 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_4659 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_4659 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_4659 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_4659 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_4659 ECTO LOOM
http://purl.obolibrary.org/obo/CHEBI_4659 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_4659 ODNAE LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#4042 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.520.150.175 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU006972 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D004221 RH-MESH LOOM
http://purl.bioontology.org/ontology/ATC/P03AA04 ATC LOOM
http://doe-generated-ontology.com/OntoAD#C0012772 ONTOAD LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000042291 PDQ LOOM