loading...| Preferred Name | apoptotic process | |
| Synonyms |
type I programmed cell death apoptosis apoptotic program signaling (initiator) caspase activity cell suicide cellular suicide apoptotic cell death programmed cell death by apoptosis apoptotic programmed cell death |
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| Definitions |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathways) which typically lead to rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. The process ends when the cell has died. The process is divided into a signaling pathway phase, and an execution phase, which is triggered by the former. |
|
| ID |
http://purl.obolibrary.org/obo/GO_0006915 |
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| database_cross_reference |
Reactome:REACT_82724 Reactome:REACT_28087 Reactome:REACT_100962 Reactome:REACT_34139 Reactome:REACT_30763 Reactome:REACT_91011 Reactome:REACT_13638 Reactome:REACT_30266 Reactome:REACT_28816 Reactome:REACT_30371 Reactome:REACT_13643 Reactome:REACT_87570 Reactome:REACT_95675 Wikipedia:Apoptosis Reactome:REACT_105149 Reactome:REACT_110081 Reactome:REACT_111964 Reactome:REACT_86749 Reactome:REACT_77415 Reactome:REACT_88784 Reactome:REACT_93937 Reactome:REACT_86873 Reactome:REACT_77313 Reactome:REACT_30361 Reactome:REACT_31349 Reactome:REACT_108651 Reactome:REACT_28795 Reactome:REACT_78802 Reactome:REACT_91243 Reactome:REACT_94099 Reactome:REACT_79809 Reactome:REACT_83328 Reactome:REACT_95069 Reactome:REACT_13526 Reactome:REACT_77132 Reactome:REACT_106672 Reactome:REACT_99799 Reactome:REACT_106405 Reactome:REACT_578 Reactome:REACT_90267 Reactome:REACT_30548 Reactome:REACT_101249 Reactome:REACT_100045 Reactome:REACT_85877 Reactome:REACT_109165 Reactome:REACT_78287 Reactome:REACT_89196 Reactome:REACT_99784 Reactome:REACT_97627 Reactome:REACT_88740 Reactome:REACT_104187 Reactome:REACT_107264 |
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| has_alternative_id |
GO:0008632 |
|
| has_broad_synonym |
cell suicide cellular suicide |
|
| has_exact_synonym |
apoptotic cell death programmed cell death by apoptosis apoptotic programmed cell death |
|
| has_narrow_synonym |
type I programmed cell death apoptosis apoptotic program |
|
| has_obo_namespace |
biological_process |
|
| has_related_synonym |
signaling (initiator) caspase activity |
|
| IAO_0000115 |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathways) which typically lead to rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. The process ends when the cell has died. The process is divided into a signaling pathway phase, and an execution phase, which is triggered by the former. |
|
| IAO_0000412 | ||
| id |
GO:0006915 |
|
| label |
apoptotic process |
|
| notation |
GO:0006915 |
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| prefLabel |
apoptotic process |
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| subClassOf |