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| Preferred Name | Fluphenazine | |
| Synonyms |
InChIKey=PLDUPXSUYLZYBN-UHFFFAOYSA-N 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-1-piperazineethanol fluphenazinum Fluorophenazine Fluorfenazine Triflumethazine fluphenazine 2-(trifluoromethyl)-10-(3-(1-(beta-hydroxyethyl)-4-piperazinyl)propyl)phenothiazine 4-(3-(2-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol 10-(3-(2-hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine C22H26F3N3OS flufenazina OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine Fluorphenazine 10-(3'-(4''-(beta-hydroxyethyl)-1''-piperazinyl)-propyl)-3-trifluoromethylphenothiazine 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol 4-(3-(-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol Fluphenazine 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethanol 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol |
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| Definitions |
A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position. A phenothiazine derivative having a trifluoromethyl subsitituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_5123 |
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| alternative term |
InChIKey=PLDUPXSUYLZYBN-UHFFFAOYSA-N 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-1-piperazineethanol fluphenazinum Fluorophenazine Fluorfenazine Triflumethazine fluphenazine 2-(trifluoromethyl)-10-(3-(1-(beta-hydroxyethyl)-4-piperazinyl)propyl)phenothiazine 4-(3-(2-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol 10-(3-(2-hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine C22H26F3N3OS flufenazina OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine Fluorphenazine 10-(3'-(4''-(beta-hydroxyethyl)-1''-piperazinyl)-propyl)-3-trifluoromethylphenothiazine 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol 4-(3-(-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol Fluphenazine 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethanol 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol
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|
| charge |
0
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| chemical has protein target |
http://purl.obolibrary.org/obo/PR_P28223 http://purl.obolibrary.org/obo/PR_P28335 http://purl.obolibrary.org/obo/PR_P10275 http://purl.obolibrary.org/obo/PR_P0DP23 |
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| chemical has protein target as antagonist | ||
| chemical inhibits protein | ||
| database_cross_reference |
KEGG DRUG:D07977 PMID:16839522 Reaxys:61643 KEGG COMPOUND:C07010 PMID:25595294 PMID:1650428 Patent:GB833474 Beilstein:1189506 Patent:US3194733 Wikipedia:Fluphenazine PMID:16117689 PMID:13950763 KEGG:C07010 Patent:US3058979 HMDB:HMDB0014761 KEGG COMPOUND:69-23-8 LINCS:LSM-3226 CiteXplore:1650428 Drug_Central:1212 CiteXplore:5128930 ChemIDplus:69-23-8 KEGG:D07977 Patent:GB829246 CAS:69-23-8 Beilstein:61643 PMID:5128930 Gmelin:1231182 NIST Chemistry WebBook:69-23-8 DrugBank:DB00623
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| definition source | ||
| formula |
C22H26F3N3OS
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|
| has exact synonym |
Fluphenazine 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethanol 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol
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| has parent hydride | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_37930 |
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| has_obo_namespace |
chebi_ontology
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|
| has_related_synonym |
InChIKey=PLDUPXSUYLZYBN-UHFFFAOYSA-N 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-1-piperazineethanol fluphenazinum Fluorophenazine Fluorfenazine Triflumethazine fluphenazine 2-(trifluoromethyl)-10-(3-(1-(beta-hydroxyethyl)-4-piperazinyl)propyl)phenothiazine 4-(3-(2-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol 10-(3-(2-hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine C22H26F3N3OS flufenazina OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine Fluorphenazine 10-(3'-(4''-(beta-hydroxyethyl)-1''-piperazinyl)-propyl)-3-trifluoromethylphenothiazine 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol 4-(3-(-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol
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|
| has_RxCUI |
4496
|
|
| id |
CHEBI:5123
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| imported from | ||
| in subset | ||
| inchi |
InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2
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|
| inchikey |
PLDUPXSUYLZYBN-UHFFFAOYSA-N
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|
| label |
Fluphenazine fluphenazine
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|
| mass |
437.52200
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| monoisotopicmass |
437.17487
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|
| notation |
CHEBI:5123
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| prefLabel |
Fluphenazine
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| smiles |
OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1
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| textual definition |
A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position. A phenothiazine derivative having a trifluoromethyl subsitituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position.
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|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_46845 |
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