Preferred Name |
dextromethorphan |
|
Synonyms |
(4aS,10S,10aS)-6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan D-methorphan (+)-dextromethorphan Balminil DM (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan d-Methorphan destrometerfano dextromethorphan dextromethorphane (+)-3-methoxy-N-methylmorphinan dextromethorphanum dextrometorfano Dextromorphan dextromethorfan Albutussin Antussan BA 2666 BA-2666 Benylin DM Calmylin DXM Delsym Medicon Romilar Tusilan |
|
Definitions |
A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough. |
|
ID |
http://purl.obolibrary.org/obo/CHEBI_4470 |
|
charge |
0 |
|
chemical binds protein | ||
database_cross_reference |
Drug_Central:842 KEGG:D03742 PMID:17573115 PMID:8158182 PMID:12711372 PMID:15505150 PMID:7976530 DrugBank:DB00514 PMID:9705419 LINCS:LSM-2726 KEGG:C06947 CAS:125-71-3 PMID:18160193 PMID:18198471 PMID:2660263 Reaxys:88549 PMID:31094746 Wikipedia:Dextromethorphan PMID:24269965 PMID:17461892 PMID:10869398 PMID:17157116 HMDB:HMDB0001920 |
|
definition source |
Reference: PMID: 17689532 |
|
formula |
C18H25NO |
|
has exact synonym |
(4aS,10S,10aS)-6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan |
|
has functional parent | ||
has role |
http://purl.obolibrary.org/obo/CHEBI_35703 http://purl.obolibrary.org/obo/CHEBI_50910 http://purl.obolibrary.org/obo/CHEBI_78298 http://purl.obolibrary.org/obo/CHEBI_60643 http://purl.obolibrary.org/obo/CHEBI_50266 |
|
has_alternative_id |
CHEBI:92579 |
|
has_obo_namespace |
chebi_ontology |
|
has_related_synonym |
D-methorphan 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan (+)-dextromethorphan Balminil DM (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan d-Methorphan destrometerfano dextromethorphan dextromethorphane (+)-3-methoxy-N-methylmorphinan dextromethorphanum dextrometorfano Dextromorphan dextromethorfan Albutussin Antussan BA 2666 BA-2666 Benylin DM Calmylin DXM Delsym Medicon Romilar Tusilan |
|
has_role | ||
id |
CHEBI:4470 |
|
imported from | ||
in subset | ||
inchi |
InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1 |
|
inchikey |
MKXZASYAUGDDCJ-NJAFHUGGSA-N |
|
is enantiomer of | ||
label |
dextromethorphan |
|
mass |
271.404 |
|
monoisotopicmass |
271.19361 |
|
notation |
CHEBI:4470 |
|
prefLabel |
dextromethorphan |
|
smiles |
C=1C=2C[C@H]3[C@@]4([C@](C2C=C(C1)OC)(CCCC4)CCN3C)[H] |
|
textual definition |
A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough. |
|
subClassOf |
This ontology integrates with OntoloBridge, allowing community users to suggest additions to the public ontology. Complete the template below to submit a term request directly to the ontology maintainer.
Term Label (required)
Suggested term name. If a term can be described with multiple synonyms, only list the preferred name here.
Term description (required)
A brief definition, description, or usage of your suggested term. Additional term synonyms may be listed in this section.
Superclass (required)
The parent term of the suggested term. The parent term should be an existing entry of the current ontology. The superclass can be selected directly from Bioportal's Classes tree viewer.
References (optional)
Provide evidence for the existence of the requested term such as Pubmed IDs of papers or links to other resources that describe the term.
Justification (optional)
Provide any additional information about the requested term here.