loading...| Preferred Name |
craniorachischisis |
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| Synonyms |
CRN |
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| Definitions |
the most severe form of neural tube defect leaving the neural tube open from the midbrain or rostral hindbrain to the base of the spine; in mammals, craniorachischisis arises as a failure of a de novo closure event occurring during primary neurulation at the boundary of the future hindbrain and cervical spine (day 22 postfertilization in humans and E8.5 in mice); craniorachischisis totalis, the most complete form of craniorachischisis, presents anencephaly and total spina bifida together and is lethal |
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| ID |
http://purl.obolibrary.org/obo/MP_0008784 |
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| definition |
the most severe form of neural tube defect leaving the neural tube open from the midbrain or rostral hindbrain to the base of the spine; in mammals, craniorachischisis arises as a failure of a de novo closure event occurring during primary neurulation at the boundary of the future hindbrain and cervical spine (day 22 postfertilization in humans and E8.5 in mice); craniorachischisis totalis, the most complete form of craniorachischisis, presents anencephaly and total spina bifida together and is lethal |
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| has_exact_synonym |
CRN |
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| has_obo_namespace |
MPheno.ontology |
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| id |
MP:0008784 |
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| label |
craniorachischisis |
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| notation |
MP:0008784 |
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| prefLabel |
craniorachischisis |
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| subClassOf |