loading...| Preferred Name | sclerosing cholangitis | |
| Synonyms |
primary sclerosing cholangitis primary sclerosing cholangitis (PSC) Primary sclerosing cholangitis cholangitis, sclerosing sclerosing cholangitis (disease) fibrosing cholangitis sclerosing cholangitis |
|
| Definitions |
A chronic, autoimmune inflammatory liver disorder characterized by narrowing and scarring of the lumen of the bile ducts. It is often seen in patients with ulcerative colitis. Signs and symptoms include jaundice, fatigue, and malabsorption. It may lead to cirrhosis and liver failure. Chronic inflammatory disease of the BILIARY TRACT. It is characterized by fibrosis and hardening of the intrahepatic and extrahepatic biliary ductal systems leading to bile duct strictures, CHOLESTASIS, and eventual BILIARY CIRRHOSIS. |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0004268 |
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| database_cross_reference |
NANDO:2100265 MedDRA:10039717 SNOMEDCT:235917005 UMLS:C0008313 SCTID:235917005 MEDGEN:3036 MeSH:D015209 MONDO:0018646 OMIM:617394 NANDO:1200440 Orphanet:447771 DOID:14268 GARD:21868 HP:0030991 NCIT:C4828 NCIt:C4828 |
|
| definition |
A chronic, autoimmune inflammatory liver disorder characterized by narrowing and scarring of the lumen of the bile ducts. It is often seen in patients with ulcerative colitis. Signs and symptoms include jaundice, fatigue, and malabsorption. It may lead to cirrhosis and liver failure. Chronic inflammatory disease of the BILIARY TRACT. It is characterized by fibrosis and hardening of the intrahepatic and extrahepatic biliary ductal systems leading to bile duct strictures, CHOLESTASIS, and eventual BILIARY CIRRHOSIS. |
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| disease has location | ||
| gwas_trait |
true |
|
| has_exact_synonym |
primary sclerosing cholangitis primary sclerosing cholangitis (PSC) Primary sclerosing cholangitis cholangitis, sclerosing sclerosing cholangitis (disease) fibrosing cholangitis sclerosing cholangitis |
|
| IAO_0000589 |
sclerosing cholangitis (disease) |
|
| id |
EFO:0004268 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_group_of_disorders http://purl.obolibrary.org/obo/mondo/mondo-base#disease_grouping |
|
| label |
sclerosing cholangitis |
|
| notation |
EFO:0004268 |
|
| preferred label |
sclerosing cholangitis |
|
| prefLabel |
sclerosing cholangitis |
|
| skos_exactMatch |
http://identifiers.org/snomedct/235917005 http://purl.obolibrary.org/obo/Orphanet_447771 http://identifiers.org/medgen/3036 http://purl.obolibrary.org/obo/NCIT_C4828 http://purl.obolibrary.org/obo/DOID_14268 |
|
| term editor |
Dani Welter |
|
| subClassOf |