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Cell Culture Ontology
Last uploaded:
July 23, 2014
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| Preferred Name | thrombin | |
| Synonyms |
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| Definitions |
Thrombin is a "trypsin-like" serine protease protein that in humans is encoded by the F2 gene.[2][3] Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the stemming of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. |
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| ID |
http://www.ebi.ac.uk/efo/EFO_0003183 |
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| database_cross_reference |
SNOMEDCT:36176003 MeSH:D013917 NCIt:C87773 OMIM:176930 DSSTox_Generic_SID:40626 SNOMEDCT:415715002
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| definition |
Thrombin is a "trypsin-like" serine protease protein that in humans is encoded by the F2 gene.[2][3] Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the stemming of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions.
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| definition_citation | ||
| label |
thrombin
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| preferred label |
thrombin
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| prefixIRI |
efo:EFO_0003183
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| prefLabel |
thrombin
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| term editor |
Tomasz Adamusiak Ele Holloway James Malone
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