loading...| Preferred Name | myelodysplastic syndrome | |
| Synonyms |
myelodysplastic syndrome, susceptibility to myelodysplasia dysmyelopoietic syndrome MDS, unclassifiable smoldering leukemia myelodysplastic syndrome myelodysplastic syndromes oligoblastic leukaemia myelodysplastic syndrome/neoplasm myelodysplastic syndrome, somatic myelodysplastic neoplasm myelodysplastic syndrome, unclassifiable Myelodysplastic Syndromes hematopoeitic - myelodysplastic syndrome (MDS) smouldering leukaemia preleukemia oligoblastic leukemia MDS MDS-U |
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| Definitions |
A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0000198 |
|
| closeMatch |
http://identifiers.org/mesh/D011289 http://linkedlifedata.com/resource/umls/id/C0026986 |
|
| database_cross_reference |
DOID:0050908 OMIM:614286 ICD9:238.75 NANDO:2100003 EFO:0000198 MedDRA:10068361 UMLS:C0033027 SCTID:109995007 MedDRA:10028532 UMLS:C3463824 ONCOTREE:MDS MONDO:0018881 GARD:0007132 MEDGEN:483005 COHD:138994 Orphanet:52688 NANDO:2200019 ICDO:9989/3 GARD:7132 ICD9:238.7 NCIT:C3247 NORD:1480 |
|
| definition |
A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) |
|
| exactMatch |
http://linkedlifedata.com/resource/umls/id/C0033027 http://identifiers.org/meddra/10028532 http://identifiers.org/omim/614286 http://purl.obolibrary.org/obo/DOID_0050908 http://linkedlifedata.com/resource/umls/id/C0026985 http://identifiers.org/mesh/D009190 http://linkedlifedata.com/resource/umls/id/C3463824 |
|
| gwas_trait |
true |
|
| has_exact_synonym |
myelodysplasia dysmyelopoietic syndrome MDS, unclassifiable smoldering leukemia myelodysplastic syndrome myelodysplastic syndromes oligoblastic leukaemia myelodysplastic syndrome/neoplasm myelodysplastic syndrome, somatic myelodysplastic neoplasm myelodysplastic syndrome, unclassifiable Myelodysplastic Syndromes hematopoeitic - myelodysplastic syndrome (MDS) smouldering leukaemia preleukemia oligoblastic leukemia MDS MDS-U |
|
| has_related_synonym |
myelodysplastic syndrome, susceptibility to |
|
| IAO_0000233 | ||
| id |
EFO:0000198 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_group_of_disorders http://purl.obolibrary.org/obo/mondo/mondo-base#disease_grouping http://purl.obolibrary.org/obo/mondo/mondo-base#nord_rare http://purl.obolibrary.org/obo/mondo#disease_grouping http://purl.obolibrary.org/obo/mondo#ordo_group_of_disorders |
|
| label |
myelodysplastic syndrome |
|
| notation |
EFO:0000198 |
|
| preferred label |
myelodysplastic syndrome |
|
| prefLabel |
myelodysplastic syndrome |
|
| skos_closeMatch | ||
| skos_exactMatch |
http://purl.obolibrary.org/obo/Orphanet_52688 http://identifiers.org/medgen/483005 http://purl.obolibrary.org/obo/EFO_0000198 http://purl.obolibrary.org/obo/DOID_0050908 http://linkedlifedata.com/resource/umls/id/C3463824 |
|
| subClassOf |
http://www.orpha.net/ORDO/Orphanet_322126 |