loading...| Preferred Name | tuberculosis | |
| Synonyms |
active tuberculosis Kochs disease TB tuberculosis disease |
|
| Definitions |
A chronic, recurrent infection caused by the bacterium Mycobacterium tuberculosis. Tuberculosis (TB) may affect almost any tissue or organ of the body with the lungs being the most common site of infection. The clinical stages of TB are primary or initial infection, latent or dormant infection, and recrudescent or adult-type TB. Ninety to 95% of primary TB infections may go unrecognized. Histopathologically, tissue lesions consist of granulomas which usually undergo central caseation necrosis. Local symptoms of TB vary according to the part affected; acute symptoms include hectic fever, sweats, and emaciation; serious complications include granulomatous erosion of pulmonary bronchi associated with hemoptysis. If untreated, progressive TB may be associated with a high degree of mortality. This infection is frequently observed in immunocompromised individuals with AIDS or a history of illicit IV drug use. |
|
| ID |
http://purl.obolibrary.org/obo/MONDO_0018076 |
|
| database_cross_reference |
icd11.foundation:2072728114 ICD9:017.96 ICD9:017.94 ICD9:017.92 ICD9:017.90 SCTID:56717001 UMLS:C0041296 MEDGEN:22513 ICD10CM:A15-A19 MESH:D014376 MedDRA:10044755 Orphanet:3389 DOID:399 GARD:7827 NCIT:C3423 NORD:1801 |
|
| definition |
A chronic, recurrent infection caused by the bacterium Mycobacterium tuberculosis. Tuberculosis (TB) may affect almost any tissue or organ of the body with the lungs being the most common site of infection. The clinical stages of TB are primary or initial infection, latent or dormant infection, and recrudescent or adult-type TB. Ninety to 95% of primary TB infections may go unrecognized. Histopathologically, tissue lesions consist of granulomas which usually undergo central caseation necrosis. Local symptoms of TB vary according to the part affected; acute symptoms include hectic fever, sweats, and emaciation; serious complications include granulomatous erosion of pulmonary bronchi associated with hemoptysis. If untreated, progressive TB may be associated with a high degree of mortality. This infection is frequently observed in immunocompromised individuals with AIDS or a history of illicit IV drug use. |
|
| has_exact_synonym |
tuberculosis disease |
|
| has_narrow_synonym |
active tuberculosis |
|
| has_related_synonym |
Kochs disease TB |
|
| id |
MONDO:0018076 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_group_of_disorders |
|
| label |
tuberculosis |
|
| notation |
MONDO:0018076 |
|
| preferred label |
tuberculosis |
|
| prefLabel |
tuberculosis |
|
| see also |
https://rarediseases.info.nih.gov/diseases/7827/tuberculosis |
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| skos_closeMatch | ||
| skos_exactMatch |
http://identifiers.org/snomedct/56717001 http://purl.obolibrary.org/obo/mondo/sources/icd11foundation/2072728114 http://purl.obolibrary.org/obo/DOID_399 http://purl.obolibrary.org/obo/Orphanet_3389 http://identifiers.org/medgen/22513 http://linkedlifedata.com/resource/umls/id/C0041296 http://purl.obolibrary.org/obo/NCIT_C3423 |
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| disjointWith | ||
| subClassOf |