loading...| Preferred Name |
Crohn's disease |
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| Synonyms |
pediatric Crohn's disease granulomatous colitis Crohn's disease of large bowel Ileitis, Regional Crohn Disease Ileitis, Terminal paediatric Crohn's disease Colitis, Granulomatous Enteritis, Regional Ileocolitis Crohns Disease regional enteritis Gastritis Associated with Crohn's Disease Crohn's associated gastritis Gastritis Associated with Crohn Disease Crohn disease Crohn's disease Crohn's disease of colon Enteritis, Granulomatous CROHN DIS CROHNS DIS |
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| Definitions |
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients. A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement. |
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| ID |
http://www.ebi.ac.uk/efo/EFO_0000384 |
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| database cross reference |
Orphanet:206 MONDO:0005011 SNOMEDCT:34000006 MeSH:D003424 UMLS:C0010346 NCIt:C27837 SCTID:7620006 UMLS:CN043071 SCTID:34000006 MedDRA:10011401 OMIM:266600 MESH:D003424 DOID:8778 ICD10:K50 ICD9:555.1 NCIT:C2965 NCIt:C2965 |
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| exactMatch |
http://identifiers.org/mesh/D003424 http://linkedlifedata.com/resource/umls/id/C0010346 http://identifiers.org/snomedct/7620006 http://purl.obolibrary.org/obo/DOID_8778 |
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| fromOldVersion |
yes |
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| gwas_trait |
true |
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| hasExactSynonym |
pediatric Crohn's disease granulomatous colitis Crohn's disease of large bowel Ileitis, Regional Crohn Disease Ileitis, Terminal paediatric Crohn's disease Colitis, Granulomatous Enteritis, Regional Ileocolitis Crohns Disease regional enteritis Gastritis Associated with Crohn's Disease Crohn's associated gastritis Gastritis Associated with Crohn Disease Crohn disease Crohn's disease Crohn's disease of colon Enteritis, Granulomatous CROHN DIS CROHNS DIS |
|
| id |
EFO:0000384 |
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| imported from | ||
| in subset |
http://purl.oboInOwllibrary.org/oboInOwl/mondo#rare http://purl.oboInOwllibrary.org/oboInOwl/mondo#orphanet_rare |
|
| label |
Crohn's disease |
|
| notation |
EFO:0000384 |
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| prefLabel |
Crohn's disease |
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| term editor |
Tomasz Adamusiak James Malone |
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| textual definition |
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients. A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement. |
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| subClassOf |