loading...| Preferred Name |
Diffuse Large B-Cell Lymphoma |
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| Synonyms |
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| Definitions |
A non-Hodgkin lymphoma characterized by a diffuse proliferation of predominantly large neoplastic B lymphocytes. It is the most frequently seen type of non-Hodgkin lymphoma, representing 30%-40% of the cases. Morphologic variants include centroblastic lymphoma, immunoblastic lymphoma, and anaplastic lymphoma. Subtypes/entities include T-cell/histiocyte rich large B-cell lymphoma, primary diffuse large B-cell lymphoma of the central nervous system, plasmablastic lymphoma, primary cutaneous diffuse large B-cell lymphoma, leg type, and ALK-positive large B-cell lymphoma. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C8851 |
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| ALT_DEFINITION |
A type of B-cell non-Hodgkin lymphoma (cancer of the immune system) that is usually aggressive (fast-growing). It is the most common type of non-Hodgkin lymphoma, and is marked by rapidly growing tumors in the lymph nodes, spleen, liver, bone marrow, or other organs. Other symptoms include fever, night sweats, and weight loss. There are several subtypes of diffuse large B-cell lymphoma. |
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| code |
C8851 |
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| Contributing_Source |
Cellosaurus CPTAC CTEP CTRP GDC |
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| definition |
A non-Hodgkin lymphoma characterized by a diffuse proliferation of predominantly large neoplastic B lymphocytes. It is the most frequently seen type of non-Hodgkin lymphoma, representing 30%-40% of the cases. Morphologic variants include centroblastic lymphoma, immunoblastic lymphoma, and anaplastic lymphoma. Subtypes/entities include T-cell/histiocyte rich large B-cell lymphoma, primary diffuse large B-cell lymphoma of the central nervous system, plasmablastic lymphoma, primary cutaneous diffuse large B-cell lymphoma, leg type, and ALK-positive large B-cell lymphoma. |
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| Display_Name |
Diffuse Large B-Cell Lymphoma |
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| ICD-O-3_Code |
9680/3 |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C158520 http://purl.obolibrary.org/obo/NCIT_C102905 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C103133 http://purl.obolibrary.org/obo/NCIT_C156952 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C126659 http://purl.obolibrary.org/obo/NCIT_C165258 http://purl.obolibrary.org/obo/NCIT_C118168 |
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| Is_Value_For_GDC_Property |
http://purl.obolibrary.org/obo/NCIT_C177615 |
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| label |
Diffuse Large B-Cell Lymphoma |
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| Legacy Concept Name |
Diffuse_Large_B-Cell_Lymphoma |
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| Maps_To |
Diffuse large B-cell lymphoma, lymph nodes of multiple sites Malignant lymphoma, large cell, diffuse, NOS Diffuse large B-cell lymphoma, intrathoracic lymph nodes Diffuse large B-cell lymphoma, intra-abdominal lymph nodes Non-follicular lymphoma Diffuse large B-cell lymphoma, extranodal and solid organ sites Malignant lymphoma, histiocytic, NOS Malignant lymphoma, large cell, cleaved and noncleaved Diffuse large B-cell lymphoma Diffuse Large B-Cell Lymphoma (DLBCL) Other non-follicular lymphoma, extranodal and solid organ sites Diffuse large B-cell lymphoma, unspecified site Diffuse large B-cell lymphoma, lymph nodes of head, face, and neck 9680/3 |
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| Neoplastic_Status |
Malignant |
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| Preferred_Name |
Diffuse Large B-Cell Lymphoma |
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| prefixIRI |
NCIT:C8851 |
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| prefLabel |
Diffuse Large B-Cell Lymphoma |
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| Semantic_Type |
Neoplastic Process |
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| UMLS_CUI |
C0079744 |
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| subClassOf |