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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Esketamine | |
| Synonyms |
|
|
| Definitions |
A cyclohexanone derivative and S-enantiomer of racemic ketamine, with analgesic, anesthetic and antidepressant activities. Although the mechanism of action is not fully understood, upon administration, esketamine targets, non-competitively binds to, and blocks N-methyl D-aspartate (NMDA) receptors. This reduces pain perception, induces sedation, and produce dissociative anesthesia. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C81400 |
|
| CAS_Registry |
33643-46-8
|
|
| CHEBI_ID |
CHEBI:60799
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|
| Chemical_Formula |
C13H16ClNO
|
|
| code |
C81400
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|
| Contributing_Source |
FDA
|
|
| definition |
A cyclohexanone derivative and S-enantiomer of racemic ketamine, with analgesic, anesthetic and antidepressant activities. Although the mechanism of action is not fully understood, upon administration, esketamine targets, non-competitively binds to, and blocks N-methyl D-aspartate (NMDA) receptors. This reduces pain perception, induces sedation, and produce dissociative anesthesia.
|
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| FDA_UNII_Code |
50LFG02TXD
|
|
| in_subset | ||
| label |
Esketamine
|
|
| Legacy Concept Name |
Esketamine
|
|
| Preferred_Name |
Esketamine
|
|
| prefixIRI |
NCIT:C81400
|
|
| prefLabel |
Esketamine
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C2825616
|
|
| subClassOf |
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