loading...| Preferred Name |
Fenfluramine Hydrochloride |
|
| Synonyms |
|
|
| Definitions |
The hydrochloride salt of fenfluramine, an amphetamine derivative and a sympathomimetic stimulant with appetite-suppressant properties. Fenfluramine, which was part of the Fen-Phen anti-obesity medication, stimulates the release of serotonin from vesicular storage, and modulates serotonin transporter function. Since serotonin regulates mood and appetite, among other functions, increased serotonin level results in a feeling of fullness and loss of appetite. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C75112 |
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| Accepted_Therapeutic_Use_For |
treatment of seizures associated with Dravet syndrome in patients 2 years of age and older |
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| CAS_Registry |
404-82-0 |
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| CHEBI_ID |
CHEBI:59729 |
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| Chemical_Formula |
C12H16F3N.HCl |
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| code |
C75112 |
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| Contributing_Source |
FDA |
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| definition |
The hydrochloride salt of fenfluramine, an amphetamine derivative and a sympathomimetic stimulant with appetite-suppressant properties. Fenfluramine, which was part of the Fen-Phen anti-obesity medication, stimulates the release of serotonin from vesicular storage, and modulates serotonin transporter function. Since serotonin regulates mood and appetite, among other functions, increased serotonin level results in a feeling of fullness and loss of appetite. |
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| FDA_UNII_Code |
3KC089243P |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Fenfluramine Hydrochloride |
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| Legacy Concept Name |
Fenfluramine_Hydrochloride |
|
| Preferred_Name |
Fenfluramine Hydrochloride |
|
| prefixIRI |
NCIT:C75112 |
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| prefLabel |
Fenfluramine Hydrochloride |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0282179 |
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| subClassOf |