loading...| Preferred Name |
Nodular Lymphocyte Predominant Hodgkin Lymphoma |
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| Synonyms |
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| Definitions |
A monoclonal B-cell neoplasm characterized by a nodular, or a nodular and diffuse proliferation of scattered large neoplastic cells known as popcorn or lymphocyte predominant cells (LP cells)- formerly called L&H cells for lymphocytic and/or histiocytic Reed-Sternberg cell variants. The LP cells lack CD15 and CD30 in nearly all instances. Patients are predominantly male, frequently in the 30-50 year age group. Most patients present with limited stage disease (localized peripheral lymphadenopathy, stage I or II). (WHO 2008) |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C7258 |
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| ALT_DEFINITION |
A rare type of Hodgkin lymphoma, which is a cancer of the immune system. It is marked by the presence of a type of cell called a popcorn cell, which is different from the typical Reed-Sternberg cell found in classical Hodgkin lymphoma. This type of Hodgkin lymphoma may change into diffuse large B-cell lymphoma. |
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| code |
C7258 |
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| Contributing_Source |
Cellosaurus CPTAC CTEP CTRP GDC PCDC |
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| definition |
A monoclonal B-cell neoplasm characterized by a nodular, or a nodular and diffuse proliferation of scattered large neoplastic cells known as popcorn or lymphocyte predominant cells (LP cells)- formerly called L&H cells for lymphocytic and/or histiocytic Reed-Sternberg cell variants. The LP cells lack CD15 and CD30 in nearly all instances. Patients are predominantly male, frequently in the 30-50 year age group. Most patients present with limited stage disease (localized peripheral lymphadenopathy, stage I or II). (WHO 2008) |
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| Display_Name |
Nodular Lymphocyte Predominant Hodgkin Lymphoma |
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| ICD-O-3_Code |
9659/3 |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C168658 http://purl.obolibrary.org/obo/NCIT_C168656 http://purl.obolibrary.org/obo/NCIT_C168657 http://purl.obolibrary.org/obo/NCIT_C168655 http://purl.obolibrary.org/obo/NCIT_C158520 http://purl.obolibrary.org/obo/NCIT_C102905 http://purl.obolibrary.org/obo/NCIT_C186341 http://purl.obolibrary.org/obo/NCIT_C168662 http://purl.obolibrary.org/obo/NCIT_C168661 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/ncit#oncotree_slim http://purl.obolibrary.org/obo/NCIT_C103135 http://purl.obolibrary.org/obo/NCIT_C156952 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C126659 http://purl.obolibrary.org/obo/NCIT_C165258 http://purl.obolibrary.org/obo/NCIT_C118168 http://purl.obolibrary.org/obo/NCIT_C157711 |
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| Is_Value_For_GDC_Property | ||
| label |
Nodular Lymphocyte Predominant Hodgkin Lymphoma |
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| Legacy Concept Name |
Nodular_Lymphocyte_Predominant_Hodgkin_s_Lymphoma |
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| Maps_To |
Hodgkin's disease, lymphocytic-histiocytic predominance involving lymph nodes of head, face, and neck Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of inguinal region and lower limb Nodular lymphocyte predominant Hodgkin lymphoma, unspecified site Hodgkin lymphoma, nodular lymphocyte predominance Nodular lymphocyte predominant Hodgkin lymphoma Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of head, face, and neck Hodgkin's disease, lymphocytic-histiocytic predominance involving lymph nodes of axilla and upper limb Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of axilla and upper limb Hodgkin lymphoma, nodular lymphocyte predominant Hodgkin lymphoma, lymphocyte predominance, nodular Hodgkin's disease, lymphocytic-histiocytic predominance involving lymph nodes of multiple sites Hodgkin's disease, lymphocytic-histiocytic predominance Hodgkin's disease, lymphocytic-histiocytic predominance, unspecified site, extranodal and solid organ sites Hodgkin's disease, lymphocytic-histiocytic predominance involving lymph nodes of inguinal region and lower limb Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of multiple sites 9659/3 |
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| Neoplastic_Status |
Malignant |
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| Preferred_Name |
Nodular Lymphocyte Predominant Hodgkin Lymphoma |
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| prefixIRI |
NCIT:C7258 |
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| prefLabel |
Nodular Lymphocyte Predominant Hodgkin Lymphoma |
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| Semantic_Type |
Neoplastic Process |
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| UMLS_CUI |
C1334968 |
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| subClassOf |