loading...| Preferred Name |
Localized Scleroderma |
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| Synonyms |
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| Definitions |
A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. Localized scleroderma typically affects the skin, with formation of patches or lines of thick and unyielding tissue; there can be muscle and underlying tissue involvement as well as occasional joint complications. The affected areas of skin can be restrictive and disfiguring. The shape, depth and location of the affected area is used to classify one of the four types of local scleroderma. An individual can have a combination of localized scleroderma types. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C72069 |
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| ALT_DEFINITION |
An autoimmune disorder marked by excessive production of collagen resulting in hardening and thickening of skin, with formation of patches or lines of thick and unyielding tissue. There can also be musculoskeletal and underlying tissue involvement. The affected areas of skin can be restrictive and disfiguring. |
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| code |
C72069 |
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| Contributing_Source |
CTRP MedDRA NICHD |
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| definition |
A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. Localized scleroderma typically affects the skin, with formation of patches or lines of thick and unyielding tissue; there can be muscle and underlying tissue involvement as well as occasional joint complications. The affected areas of skin can be restrictive and disfiguring. The shape, depth and location of the affected area is used to classify one of the four types of local scleroderma. An individual can have a combination of localized scleroderma types. |
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| Display_Name |
Localized Scleroderma |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C90259 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C118468 |
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| label |
Localized Scleroderma |
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| Legacy Concept Name |
Localized_Scleroderma |
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| Maps_To |
Morphea |
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| Preferred_Name |
Localized Scleroderma |
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| prefixIRI |
NCIT:C72069 |
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| prefLabel |
Localized Scleroderma |
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| Semantic_Type |
Disease or Syndrome |
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| UMLS_CUI |
C0036420 |
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| subClassOf |