loading...| Preferred Name |
Hetacillin Potassium |
|
| Synonyms |
|
|
| Definitions |
The potassium salt of hetacillin, a semi-synthetic penicillin antibiotic with bactericidal activity. Hetacillin is a prodrug that is converted to ampicillin via esterases. Ampicillin binds to and inactivated penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C65845 |
|
| CAS_Registry |
5321-32-4 |
|
| CHEBI_ID |
CHEBI:34789 |
|
| Chemical_Formula |
C19H22N3O4S.K |
|
| code |
C65845 |
|
| Contributing_Source |
FDA |
|
| definition |
The potassium salt of hetacillin, a semi-synthetic penicillin antibiotic with bactericidal activity. Hetacillin is a prodrug that is converted to ampicillin via esterases. Ampicillin binds to and inactivated penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis. |
|
| FDA_UNII_Code |
95PFX5932Y |
|
| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Hetacillin Potassium |
|
| Legacy Concept Name |
Hetacillin_Potassium |
|
| Preferred_Name |
Hetacillin Potassium |
|
| prefixIRI |
NCIT:C65845 |
|
| prefLabel |
Hetacillin Potassium |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0812398 |
|
| subClassOf |