Preferred Name

Thrombotic Microangiopathy

Synonyms
Definitions

A microvascular coagulopathy that may result from systemic vascular endothelial injury triggering the development of a procoagulant state, activation of the complement cascade, and microthrombi formation. Signs may include hemolytic anemia, thrombocytopenia, hypertension and renal dysfunction.

ID

http://purl.obolibrary.org/obo/NCIT_C62605

ALT_DEFINITION

The syndromes of microangiopathic hemolytic anemia, thrombocytopenia, and variable signs of organ impairment, due to platelet aggregation in the microcirculation.

code

C62605

Contributing_Source

NICHD

definition

A microvascular coagulopathy that may result from systemic vascular endothelial injury triggering the development of a procoagulant state, activation of the complement cascade, and microthrombi formation. Signs may include hemolytic anemia, thrombocytopenia, hypertension and renal dysfunction.

in_subset

http://purl.obolibrary.org/obo/NCIT_C90259

http://purl.obolibrary.org/obo/NCIT_C132009

label

Thrombotic Microangiopathy

Legacy Concept Name

Thrombotic_Microangiopathy

Preferred_Name

Thrombotic Microangiopathy

prefixIRI

NCIT:C62605

prefLabel

Thrombotic Microangiopathy

Semantic_Type

Disease or Syndrome

UMLS_CUI

C2717961

subClassOf

http://purl.obolibrary.org/obo/NCIT_C2902

http://purl.obolibrary.org/obo/NCIT_C180553

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