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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Methadone | |
| Synonyms |
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| Definitions |
A synthetic opioid with analgesic activity. Methadone mimics the actions of endogenous peptides at CNS opioid receptors, primarily on the mu-receptor and has actions similar to those of morphine and morphine-like agents. The characteristic morphine-like effects include analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia and physical dependence. However, the detoxification symptoms between morphine-like agents and methadone differ in that the onset of methadone's withdrawal symptoms is slower, the course is more prolonged and the symptoms are less severe. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C62044 |
|
| CAS_Registry |
76-99-3
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| CHEBI_ID |
CHEBI:6807
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| Chemical_Formula |
C21H27NO
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| code |
C62044
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| Contributing_Source |
CTRP FDA
|
|
| definition |
A synthetic opioid with analgesic activity. Methadone mimics the actions of endogenous peptides at CNS opioid receptors, primarily on the mu-receptor and has actions similar to those of morphine and morphine-like agents. The characteristic morphine-like effects include analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia and physical dependence. However, the detoxification symptoms between morphine-like agents and methadone differ in that the onset of methadone's withdrawal symptoms is slower, the course is more prolonged and the symptoms are less severe.
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| Display_Name |
Methadone
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|
| FDA_UNII_Code |
UC6VBE7V1Z
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| Has_Salt_Form | ||
| Has_Target | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 |
|
| label |
Methadone
|
|
| Legacy Concept Name |
Methadone_Base
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|
| Preferred_Name |
Methadone
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|
| prefixIRI |
NCIT:C62044
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| prefLabel |
Methadone
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| Semantic_Type |
Organic Chemical Pharmacologic Substance
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| UMLS_CUI |
C0025605
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| subClassOf |
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