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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Paromomycin | |
| Synonyms |
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| Definitions |
An aminoglycoside antibiotic derived from Streptomyces rimosus var. paromomycinus, with amebicidal and antibacterial activity. Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of translation, thereby leading to inhibition of protein synthesis followed by cell death. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C61878 |
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| CAS_Registry |
59-04-1 7542-37-2
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| CHEBI_ID |
CHEBI:7934
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| Chemical_Formula |
C23H45N5O14
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|
| code |
C61878
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| Contributing_Source |
FDA
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|
| definition |
An aminoglycoside antibiotic derived from Streptomyces rimosus var. paromomycinus, with amebicidal and antibacterial activity. Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of translation, thereby leading to inhibition of protein synthesis followed by cell death.
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| FDA_UNII_Code |
61JJC8N5ZK
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| Has_Salt_Form | ||
| in_subset | ||
| label |
Paromomycin
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|
| Legacy Concept Name |
Paromomycin
|
|
| Preferred_Name |
Paromomycin
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|
| prefixIRI |
NCIT:C61878
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| prefLabel |
Paromomycin
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0030576
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| subClassOf |
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