Preferred Name |
Methicillin |
|
Synonyms |
|
|
Definitions |
A semisynthetic, narrow spectrum beta-lactamase-resistant penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Methicillin binds to specific penicillin-binding proteins (BPBs) on the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial lysis. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C61842 |
|
CAS_Registry |
61-32-5 |
|
CHEBI_ID |
CHEBI:6827 |
|
Chemical_Formula |
C17H20N2O6S |
|
code |
C61842 |
|
Contributing_Source |
FDA |
|
definition |
A semisynthetic, narrow spectrum beta-lactamase-resistant penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Methicillin binds to specific penicillin-binding proteins (BPBs) on the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial lysis. |
|
FDA_UNII_Code |
Q91FH1328A |
|
Has_Salt_Form | ||
in_subset | ||
label |
Methicillin |
|
Legacy Concept Name |
Methicillin |
|
Preferred_Name |
Methicillin |
|
prefixIRI |
NCIT:C61842 |
|
prefLabel |
Methicillin |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0025643 |
|
subClassOf |