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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Lidocaine | |
| Synonyms |
|
|
| Definitions |
A synthetic aminoethylamide with local anesthetic and antiarrhythmic properties. Lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses and effecting local anesthesia. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C614 |
|
| Accepted_Therapeutic_Use_For |
Cardiac arrhythmias; Local anesthetic
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| ALT_DEFINITION |
A substance used to relieve pain by blocking signals at the nerve endings in skin. It can also be given intravenously to stop heart arrhythmias. It is a type of local anesthetic and antiarrhythmic.
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| CAS_Registry |
137-58-6
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| CHEBI_ID |
CHEBI:6456
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| Chemical_Formula |
C14H22N2O
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|
| code |
C614
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| Contributing_Source |
CPTAC CTRP FDA
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|
| definition |
A synthetic aminoethylamide with local anesthetic and antiarrhythmic properties. Lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses and effecting local anesthesia.
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|
| Display_Name |
Lidocaine
|
|
| FDA_UNII_Code |
98PI200987
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| Has_Salt_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C156952 http://purl.obolibrary.org/obo/NCIT_C156953 http://purl.obolibrary.org/obo/NCIT_C116977 |
|
| label |
Lidocaine
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|
| Legacy Concept Name |
Lidocaine
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|
| NCI_Drug_Dictionary_ID |
39607
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|
| NSC Number |
40030
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|
| PDQ_Closed_Trial_Search_ID |
39607
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|
| PDQ_Open_Trial_Search_ID |
39607
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|
| Preferred_Name |
Lidocaine
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|
| prefixIRI |
NCIT:C614
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|
| prefLabel |
Lidocaine
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|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
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|
| UMLS_CUI |
C0023660
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|
| subClassOf |
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