loading...| Preferred Name | Tetracycline Hydrochloride | |
| Synonyms |
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| Definitions |
The hydrochloride salt of tetracycline, a broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces aureofaciens. In bacteria, tetracycline blocks binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis and bacterial cell growth. Because naturally fluorescing tetracycline binds to newly formed bone at the bone/osteoid interface, tetracycline-labeling of bone and fluorescence microscopy may be used to perform bone histomorphometry. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C48020 |
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| CAS_Registry |
64-75-5 |
|
| Chemical_Formula |
C22H24N2O8.HCl |
|
| code |
C48020 |
|
| Contributing_Source |
CTRP FDA |
|
| definition |
The hydrochloride salt of tetracycline, a broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces aureofaciens. In bacteria, tetracycline blocks binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis and bacterial cell growth. Because naturally fluorescing tetracycline binds to newly formed bone at the bone/osteoid interface, tetracycline-labeling of bone and fluorescence microscopy may be used to perform bone histomorphometry. |
|
| Display_Name |
Tetracycline Hydrochloride |
|
| FDA_UNII_Code |
P6R62377KV |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Tetracycline Hydrochloride |
|
| Legacy Concept Name |
Tetracycline_Hydrochloride |
|
| NCI_Drug_Dictionary_ID |
42307 |
|
| PDQ_Closed_Trial_Search_ID |
42307 |
|
| PDQ_Open_Trial_Search_ID |
42307 |
|
| Preferred_Name |
Tetracycline Hydrochloride |
|
| prefixIRI |
NCIT:C48020 |
|
| prefLabel |
Tetracycline Hydrochloride |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0546879 |
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| subClassOf |