Preferred Name

Malathion
Synonyms
Definitions

A synthetic phosphorous compound and cholinesterase inhibitor that is strictly used as a topical pediculicide. Malathion exerts its action on the nervous system of the lice by irreversibly inhibiting the activity of cholinesterase, thereby allowing acetylcholine to accumulate at cholinergic synapses and enhancing cholinergic receptor stimulation. This eventually leads to the head lice's death.

ID

http://purl.obolibrary.org/obo/NCIT_C47593

ALT_DEFINITION

The organophosphorus agent malathion.

CAS_Registry

121-75-5

CHEBI_ID

CHEBI:6651

Chemical_Formula

C10H19O6PS2

code

C47593

Contributing_Source

CDISC

FDA

definition

A synthetic phosphorous compound and cholinesterase inhibitor that is strictly used as a topical pediculicide. Malathion exerts its action on the nervous system of the lice by irreversibly inhibiting the activity of cholinesterase, thereby allowing acetylcholine to accumulate at cholinergic synapses and enhancing cholinergic receptor stimulation. This eventually leads to the head lice's death.

FDA_UNII_Code

U5N7SU872W

in_subset

http://purl.obolibrary.org/obo/NCIT_C77526

http://purl.obolibrary.org/obo/NCIT_C63923

http://purl.obolibrary.org/obo/NCIT_C160930

http://purl.obolibrary.org/obo/NCIT_C61410

label

Malathion

Legacy Concept Name

Malathion

NSC Number

6524

Preferred_Name

Malathion

prefixIRI

NCIT:C47593

prefLabel

Malathion

Semantic_Type

Organic Chemical

Pharmacologic Substance

Hazardous or Poisonous Substance

UMLS_CUI

C0024547

subClassOf

http://purl.obolibrary.org/obo/NCIT_C29727

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http://purl.bioontology.org/ontology/SNOMEDCT/87205003 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU009774 LOINC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146761 NDFRT LOOM
http://purl.obolibrary.org/obo/MIRO_10000065 MIRO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.705.539.345.500 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017310 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.300.692.500 RH-MESH LOOM
http://purl.obolibrary.org/obo/dinto_DB00772 DINTO LOOM
http://purl.bioontology.org/ontology/SNMI/C-23162 SNMI LOOM
http://purl.obolibrary.org/obo/OMIT_0009369 OMIT LOOM
http://purl.bioontology.org/ontology/NDDF/002995 NDDF LOOM
http://www.co-ode.org/ontologies/galen#Malathion GALEN LOOM
http://purl.bioontology.org/ontology/LNC/LP16826-7 LOINC LOOM
http://purl.bioontology.org/ontology/VANDF/4018435 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008294 RH-MESH LOOM
https://go.drugbank.com/drugs/DB00772 MDM LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47593 NCIT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#7690 OCHV LOOM
http://purl.obolibrary.org/obo/CHEBI_6651 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_6651 PDRO LOOM
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http://purl.obolibrary.org/obo/CHEBI_6651 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6651 NIFSTD LOOM
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http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.705.400.625.500 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0024547 OCHV LOOM
http://www.drugbank.ca/drugs/DB00772 FTC LOOM
http://localhost/plosthes.2017-1#2138 PLOSTHES LOOM
http://purl.bioontology.org/ontology/ATC/P03AX03 ATC LOOM