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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Ketoprofen | |
| Synonyms |
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| Definitions |
A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C47578 |
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| CAS_Registry |
22071-15-4
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|
| CHEBI_ID |
CHEBI:6128
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| Chemical_Formula |
C16H14O3
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|
| code |
C47578
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| Contributing_Source |
CTRP FDA
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|
| definition |
A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.
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| Display_Name |
Ketoprofen
|
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| FDA_UNII_Code |
90Y4QC304K
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| Has_Target | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 |
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| label |
Ketoprofen
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|
| Legacy Concept Name |
Ketoprofen
|
|
| NCI_Drug_Dictionary_ID |
743614
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|
| PDQ_Closed_Trial_Search_ID |
743614
|
|
| PDQ_Open_Trial_Search_ID |
743614
|
|
| Preferred_Name |
Ketoprofen
|
|
| prefixIRI |
NCIT:C47578
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| prefLabel |
Ketoprofen
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0022635
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| subClassOf |
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