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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Cloxacillin Sodium | |
| Synonyms |
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| Definitions |
The sodium salt of cloxaclliin, a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity. Cloxacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C47460 |
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| CAS_Registry |
7081-44-9
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| CHEBI_ID |
CHEBI:34978
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| Chemical_Formula |
C19H17ClN3O5S.Na.H2O
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| code |
C47460
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| Contributing_Source |
FDA
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| definition |
The sodium salt of cloxaclliin, a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity. Cloxacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis.
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| FDA_UNII_Code |
65LCB00B4Y
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Cloxacillin Sodium
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|
| Legacy Concept Name |
Cloxacillin_Sodium
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|
| Preferred_Name |
Cloxacillin Sodium
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|
| prefixIRI |
NCIT:C47460
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| prefLabel |
Cloxacillin Sodium
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0037496
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| subClassOf |
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