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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Clomipramine Hydrochloride | |
| Synonyms |
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| Definitions |
The hydrochloride salt form of clomipramine, a tertiary amine salt derivative of dibenzazepine. Clomipramine hydrochloride is a tricyclic antidepressant that acts by reducing the re-uptake of norepinephrine and serotonin in the central nervous system, thereby enhancing the effects of these neurotransmitters. This drug also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which are responsible for the many side effects seen with this agent. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C47458 |
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| CAS_Registry |
17321-77-6
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| CHEBI_ID |
CHEBI:3755
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| Chemical_Formula |
C19H23ClN2.HCl
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|
| code |
C47458
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| Contributing_Source |
FDA
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| definition |
The hydrochloride salt form of clomipramine, a tertiary amine salt derivative of dibenzazepine. Clomipramine hydrochloride is a tricyclic antidepressant that acts by reducing the re-uptake of norepinephrine and serotonin in the central nervous system, thereby enhancing the effects of these neurotransmitters. This drug also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which are responsible for the many side effects seen with this agent.
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| FDA_UNII_Code |
2LXW0L6GWJ
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Clomipramine Hydrochloride
|
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| Legacy Concept Name |
Clomipramine_Hydrochloride
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| NSC Number |
169865
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| Preferred_Name |
Clomipramine Hydrochloride
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|
| prefixIRI |
NCIT:C47458
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| prefLabel |
Clomipramine Hydrochloride
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0282107
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| subClassOf |
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