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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Droperidol | |
| Synonyms |
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| Definitions |
A butyrophenone with anti-emetic, sedative and anti-anxiety properties. Although the exact mechanism through which droperidol exerts its effects is unknown, droperidol may block dopamine receptors in the chemoreceptor trigger zone (CTZ), which may lead to its anti-emetic effect. This agent may also bind to postsynaptic gamma-aminobutyric acid (GABA) receptors in the central nervous system (CNS), which increases the inhibitory effect of GABA and leads to sedative and anti-anxiety activities. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C458 |
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| ALT_DEFINITION |
A drug used to prevent nausea and vomiting in patients who receive anesthesia before surgery. It is also used to treat anxiety. Droperidol is a type of antiemetic, adjunct anesthesia, and antipsychotic.
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| CAS_Registry |
548-73-2
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| CHEBI_ID |
CHEBI:4717
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| Chemical_Formula |
C22H22FN3O2
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| code |
C458
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| Contributing_Source |
FDA
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|
| definition |
A butyrophenone with anti-emetic, sedative and anti-anxiety properties. Although the exact mechanism through which droperidol exerts its effects is unknown, droperidol may block dopamine receptors in the chemoreceptor trigger zone (CTZ), which may lead to its anti-emetic effect. This agent may also bind to postsynaptic gamma-aminobutyric acid (GABA) receptors in the central nervous system (CNS), which increases the inhibitory effect of GABA and leads to sedative and anti-anxiety activities.
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| FDA_UNII_Code |
O9U0F09D5X
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| in_subset | ||
| label |
Droperidol
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| Legacy Concept Name |
Droperidol
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| NCI_Drug_Dictionary_ID |
39227
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| NSC Number |
169874
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| PDQ_Closed_Trial_Search_ID |
39227
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| PDQ_Open_Trial_Search_ID |
39227
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| Preferred_Name |
Droperidol
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| prefixIRI |
NCIT:C458
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| prefLabel |
Droperidol
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| Semantic_Type |
Organic Chemical Pharmacologic Substance
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| UMLS_CUI |
C0013136
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| subClassOf |
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