loading...| Preferred Name |
Chlorpromazine |
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| Synonyms |
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| Definitions |
A phenothiazine and traditional antipsychotic agent with anti-emetic activity. Chlorpromazine exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain. This leads to a reduction in psychotic symptoms, such as hallucinations and delusions. Chlorpromazine appears to exert its anti-emetic activity by blocking the dopamine receptors in the chemical trigger zone (CTZ) in the brain, thereby relieving nausea and vomiting. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C367 |
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| CAS_Registry |
50-53-3 |
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| CHEBI_ID |
CHEBI:3647 |
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| Chemical_Formula |
C17H19ClN2S |
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| code |
C367 |
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| Contributing_Source |
FDA |
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| definition |
A phenothiazine and traditional antipsychotic agent with anti-emetic activity. Chlorpromazine exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain. This leads to a reduction in psychotic symptoms, such as hallucinations and delusions. Chlorpromazine appears to exert its anti-emetic activity by blocking the dopamine receptors in the chemical trigger zone (CTZ) in the brain, thereby relieving nausea and vomiting. |
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| FDA_UNII_Code |
U42B7VYA4P |
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| Has_Salt_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C173383 |
|
| label |
Chlorpromazine |
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| Legacy Concept Name |
Chlorpromazine |
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| NCI_Drug_Dictionary_ID |
39752 |
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| NSC Number |
167745 |
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| PDQ_Closed_Trial_Search_ID |
39752 |
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| PDQ_Open_Trial_Search_ID |
39752 |
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| Preferred_Name |
Chlorpromazine |
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| prefixIRI |
NCIT:C367 |
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| prefLabel |
Chlorpromazine |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0699065 |
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| subClassOf |