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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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Preferred Name | Patent Foramen Ovale | |
Synonyms |
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Definitions |
A persistent opening in the atrial septum after birth. While a normal part of fetal circulation, the foramen ovale should close once the newborn begins breathing and the pressure in the left atrium exceeds that of the right atrium. While a PFO is generally asymptomatic, it can lead to the passage of clots from the venous circulation into the artierial circulation, resulting in paradoxical emboli, and possible strokes. |
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ID |
http://purl.obolibrary.org/obo/NCIT_C34619 |
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code |
C34619
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definition |
A persistent opening in the atrial septum after birth. While a normal part of fetal circulation, the foramen ovale should close once the newborn begins breathing and the pressure in the left atrium exceeds that of the right atrium. While a PFO is generally asymptomatic, it can lead to the passage of clots from the venous circulation into the artierial circulation, resulting in paradoxical emboli, and possible strokes.
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label |
Patent Foramen Ovale
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Legacy Concept Name |
Patent_Foramen_Ovale
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Preferred_Name |
Patent Foramen Ovale
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prefixIRI |
NCIT:C34619
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prefLabel |
Patent Foramen Ovale
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Semantic_Type |
Disease or Syndrome Congenital Abnormality
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UMLS_CUI |
C4229431
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subClassOf |
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