loading...| Preferred Name | Myelodysplastic Syndrome | |
| Synonyms |
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| Definitions |
A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C3247 |
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| ALT_DEFINITION |
A group of diseases in which the bone marrow does not make enough healthy blood cells. A disorder characterized by insufficiently healthy hematapoietic cell production by the bone marrow. A pre-malignant disorder characterized by blood cytopenias and abnormalities in bone marrow morphology. |
|
| code |
C3247 |
|
| Contributing_Source |
Cellosaurus CPTAC CTEP CTRP GDC MedDRA NICHD |
|
| definition |
A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) |
|
| Display_Name |
Myelodysplastic Syndrome |
|
| ICD-O-3_Code |
9989/3 |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C138190 http://purl.obolibrary.org/obo/NCIT_C168658 http://purl.obolibrary.org/obo/NCIT_C168656 http://purl.obolibrary.org/obo/NCIT_C168657 http://purl.obolibrary.org/obo/NCIT_C168655 http://purl.obolibrary.org/obo/NCIT_C90259 http://purl.obolibrary.org/obo/NCIT_C158520 http://purl.obolibrary.org/obo/NCIT_C102905 http://purl.obolibrary.org/obo/NCIT_C168662 http://purl.obolibrary.org/obo/NCIT_C168661 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/ncit#oncotree_slim http://purl.obolibrary.org/obo/NCIT_C156952 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C118464 http://purl.obolibrary.org/obo/NCIT_C126659 http://purl.obolibrary.org/obo/NCIT_C138188 http://purl.obolibrary.org/obo/NCIT_C165258 http://purl.obolibrary.org/obo/NCIT_C118168 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C156966 |
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| Is_Value_For_GDC_Property |
http://purl.obolibrary.org/obo/NCIT_C2991 |
|
| label |
Myelodysplastic Syndrome |
|
| Legacy Concept Name |
Myelodysplastic_Syndrome |
|
| Maps_To |
High grade myelodysplastic syndrome lesions Myelodysplastic syndrome, NOS Preleukemic syndrome Myelodysplastic syndrome Myelodysplastic syndromes Preleukemia Low grade myelodysplastic syndrome lesions Myelodysplastic syndrome, unspecified Myelodysplastic Syndromes Other myelodysplastic syndromes 9989/3 |
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| Neoplastic_Status |
Malignant |
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| Preferred_Name |
Myelodysplastic Syndrome |
|
| prefixIRI |
NCIT:C3247 |
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| prefLabel |
Myelodysplastic Syndrome |
|
| Semantic_Type |
Neoplastic Process |
|
| UMLS_CUI |
C3463824 |
|
| subClassOf |
http://purl.obolibrary.org/obo/NCIT_C9290 |