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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Azlocillin | |
| Synonyms |
|
|
| Definitions |
A semisynthetic, extended spectrum acylampicillin with antibacterial activity. Azlocillin binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, thereby inhibiting the cross-linking of peptidoglycans, which are critical components of the bacterial cell wall. This prevents proper bacterial cell wall synthesis, thereby results in the weakening of the bacterial cell wall and eventually leading to cell lysis. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C293 |
|
| CAS_Registry |
37091-66-0
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|
| CHEBI_ID |
CHEBI:2956
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|
| Chemical_Formula |
C20H23N5O6S
|
|
| code |
C293
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|
| Contributing_Source |
FDA
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|
| definition |
A semisynthetic, extended spectrum acylampicillin with antibacterial activity. Azlocillin binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, thereby inhibiting the cross-linking of peptidoglycans, which are critical components of the bacterial cell wall. This prevents proper bacterial cell wall synthesis, thereby results in the weakening of the bacterial cell wall and eventually leading to cell lysis.
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| FDA_UNII_Code |
HUM6H389W0
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|
| Has_Salt_Form | ||
| in_subset | ||
| label |
Azlocillin
|
|
| Legacy Concept Name |
Azlocillin
|
|
| NCI_Drug_Dictionary_ID |
39160
|
|
| PDQ_Closed_Trial_Search_ID |
39160
|
|
| PDQ_Open_Trial_Search_ID |
39160
|
|
| Preferred_Name |
Azlocillin
|
|
| prefixIRI |
NCIT:C293
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|
| prefLabel |
Azlocillin
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic
|
|
| UMLS_CUI |
C0004499
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|
| subClassOf |
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