loading...| Preferred Name |
6-Azauridine |
|
| Synonyms |
|
|
| Definitions |
A synthetic triazine analogue of uridine with antimetabolite activity. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C291 |
|
| CAS_Registry |
54-25-1 |
|
| CHEBI_ID |
CHEBI:35668 |
|
| code |
C291 |
|
| Contributing_Source |
FDA |
|
| definition |
A synthetic triazine analogue of uridine with antimetabolite activity. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis. |
|
| FDA_UNII_Code |
7BVB29RCPR |
|
| in_subset | ||
| label |
6-Azauridine |
|
| Legacy Concept Name |
_6-Azauridine |
|
| NCI_Drug_Dictionary_ID |
39158 |
|
| NSC Number |
32074 |
|
| PDQ_Closed_Trial_Search_ID |
39158 |
|
| PDQ_Open_Trial_Search_ID |
39158 |
|
| Preferred_Name |
6-Azauridine |
|
| prefixIRI |
NCIT:C291 |
|
| prefLabel |
6-Azauridine |
|
| Semantic_Type |
Pharmacologic Substance Nucleic Acid, Nucleoside, or Nucleotide |
|
| UMLS_CUI |
C0004483 |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/CHEBI_35668 | CHEBI | LOOM | |
| http://purl.obolibrary.org/obo/CHEBI_35668 | DINTO | LOOM | |
| http://purl.obolibrary.org/obo/CHEBI_35668 | BIOMODELS | LOOM | |
| http://purl.bioontology.org/ontology/PDQ/CDR0000039158 | PDQ | LOOM | |
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C291 | NCIT | LOOM |