Preferred Name

Orotidylate Decarboxylase Inhibitor

Synonyms
Definitions

Any substance that inhibits orotidine 5'-phosphate decarboxylase (orotidylate decarboxylase), an enzyme that catalyzes the decarboxylation of orotidine monophosphate to form uridine monophosphate and is required for the de novo synthesis of uridine and pyrimidines. Inhibition of orotidine 5'-phosphate decarboxylase inhibits DNA, RNA, and protein synthesis.

ID

http://purl.obolibrary.org/obo/NCIT_C2170

code

C2170

definition

Any substance that inhibits orotidine 5'-phosphate decarboxylase (orotidylate decarboxylase), an enzyme that catalyzes the decarboxylation of orotidine monophosphate to form uridine monophosphate and is required for the de novo synthesis of uridine and pyrimidines. Inhibition of orotidine 5'-phosphate decarboxylase inhibits DNA, RNA, and protein synthesis.

label

Orotidylate Decarboxylase Inhibitor

Legacy Concept Name

Orotidylate_Decarboxylase_Inhibitor

Preferred_Name

Orotidylate Decarboxylase Inhibitor

prefixIRI

NCIT:C2170

prefLabel

Orotidylate Decarboxylase Inhibitor

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C1518619

subClassOf

http://purl.obolibrary.org/obo/NCIT_C471

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