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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Fluvoxamine Maleate | |
| Synonyms |
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| Definitions |
The maleate salt form of fluvoxamine, a 2-aminoethyl oxime ether of aralkylketones, with antidepressant, antiobsessive-compulsive, and antibulimic activities. Fluvoxamine blocks serotonin reuptake by inhibiting the serotonin reuptake pump of the presynaptic neuronal membrane leading to an increase of serotonin levels within the synaptic cleft. This results in facilitated serotonergic transmission and decreased serotonin turnover leading to antidepressant and antiobsessive-compulsive effects. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C29063 |
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| ALT_DEFINITION |
A drug used to treat obsessive-compulsive disorder. It is a type of antidepressant agent and selective serotonin reuptake inhibitor (SSRI).
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| CAS_Registry |
61718-82-9
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| Chemical_Formula |
C15H21F3N2O2.C4H4O4
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|
| code |
C29063
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| Contributing_Source |
CTRP FDA
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|
| definition |
The maleate salt form of fluvoxamine, a 2-aminoethyl oxime ether of aralkylketones, with antidepressant, antiobsessive-compulsive, and antibulimic activities. Fluvoxamine blocks serotonin reuptake by inhibiting the serotonin reuptake pump of the presynaptic neuronal membrane leading to an increase of serotonin levels within the synaptic cleft. This results in facilitated serotonergic transmission and decreased serotonin turnover leading to antidepressant and antiobsessive-compulsive effects.
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| Display_Name |
Fluvoxamine Maleate
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|
| FDA_UNII_Code |
5LGN83G74V
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C173383 http://purl.obolibrary.org/obo/NCIT_C173381 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Fluvoxamine Maleate
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| Legacy Concept Name |
Fluvoxamine_Maleate
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| NCI_Drug_Dictionary_ID |
735770
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| PDQ_Closed_Trial_Search_ID |
735770
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| PDQ_Open_Trial_Search_ID |
735770
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| Preferred_Name |
Fluvoxamine Maleate
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| prefixIRI |
NCIT:C29063
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| prefLabel |
Fluvoxamine Maleate
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0700473
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| subClassOf |
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